Evidence map›Paper›PMID 39947716›Full record

ArticleBMJ global health2025

Contextual factors influencing implementation of tuberculosis digital adherence technologies: a scoping review guided by the RE-AIM framework.

Shruti Bahukudumbi, Chimweta I Chilala, Nicola Foster, Barbie Patel, Mona S Mohamed, Miranda Zary, Cedric Kafie, Genevieve Gore, Kevin Schwartzman, Katherine L Fielding and 1 more

Abstract readScoping Review
In one paragraph

Article in BMJ global health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Shruti BahukudumbiDepartment of Public Health and Community Medicine and Center for Global Public Health, Tufts University School of Medicine, Boston, Massachusetts, USA.
Chimweta I ChilalaTB Centre, London School of Hygiene and Tropical Medicine, London, UK.ORCID http://orcid.org/0000-0001-9039-2367
Nicola FosterTB Centre, London School of Hygiene and Tropical Medicine, London, UK.
Barbie PatelDepartment of Public Health and Community Medicine and Center for Global Public Health, Tufts University School of Medicine, Boston, Massachusetts, USA.
Mona S MohamedMcGill International Tuberculosis Centre, Research Institute of the McGill University Health Centre, Montreal, Quebec, Canada.
Miranda ZaryMcGill International Tuberculosis Centre, Research Institute of the McGill University Health Centre, Montreal, Quebec, Canada.
Cedric KafieMcGill International Tuberculosis Centre, Research Institute of the McGill University Health Centre, Montreal, Quebec, Canada.
Genevieve GoreSchulich Library of Physical Sciences, Life Sciences, and Engineering, McGill University, Montreal, Quebec, Canada.ORCID http://orcid.org/0000-0003-1072-2683
Kevin SchwartzmanMcGill International Tuberculosis Centre, Research Institute of the McGill University Health Centre, Montreal, Quebec, Canada.ORCID http://orcid.org/0000-0002-3354-1159
Katherine L FieldingTB Centre, London School of Hygiene and Tropical Medicine, London, UK.ORCID http://orcid.org/0000-0002-6524-3754
Ramnath SubbaramanDepartment of Public Health and Community Medicine and Center for Global Public Health, Tufts University School of Medicine, Boston, Massachusetts, USA ramnath.sub@gmail.com.ORCID http://orcid.org/0000-0002-2063-943X

Funding

Gates Foundation INV-038215
6 · The paper itself

Abstract

introductionDigital adherence technologies (DATs) may enable person-centred tuberculosis (TB) treatment monitoring; however, implementation challenges may undermine their effectiveness. Using the reach, effectiveness, adoption, implementation and maintenance framework, we conducted a scoping review to identify contextual factors informing 'reach' (DAT engagement by people with TB) and 'adoption' (DAT uptake by healthcare providers or clinics).

methodsWe searched eight databases from 1 January 2000 to 25 April 2023 to identify all TB DAT studies. After extracting qualitative and quantitative findings, using thematic synthesis, we analysed common findings to create meta-themes informing DAT reach or adoption. Meta-themes were further organised using the Unified Theory of Acceptance and Use of Technology, which posits technology use is influenced by perceived usefulness, ease of use, social influences and facilitating conditions.

results66 reports met inclusion criteria, with 61 reporting on DAT reach among people with TB and 27 reporting on DAT adoption by healthcare providers. Meta-themes promoting reach included perceptions that DATs improved medication adherence, facilitated communication with providers, made people feel more 'cared for' and enhanced convenience compared with alternative care models (perceived usefulness) and lowered stigma (social influences). Meta-themes limiting reach included literacy and language barriers and DAT technical complexity (ease of use); increased stigma (social influences) and suboptimal DAT function and complex cellular accessibility challenges (facilitating conditions). Meta-themes promoting adoption included perceptions that DATs improved care quality or efficiency (perceived usefulness). Meta-themes limiting adoption included negative DAT impacts on workload or employment and suboptimal accuracy of adherence data (perceived usefulness); and suboptimal DAT function, complex cellular accessibility challenges and insufficient provider training (facilitating conditions). Limitations of this review include the limited studies informing adoption meta-themes.

conclusionThis review identifies diverse contextual factors that can inform improvements in DAT design and implementation to achieve higher engagement by people with TB and healthcare providers, which could improve intervention effectiveness.

Indexed as

Digital TechnologyMedication AdherenceTuberculosisHumansGlobal HealthSystematic reviewTuberculosis

Identifiers

PMID39947716
PMCPMC11831270

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.