ArticleNature communications2025
Natural variation of indels in the CTB3 promoter confers cold tolerance in japonica rice.
Article in Nature communications, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
21 citing papers in PubMed.
- OsbHLH6 regulates OsMADS57 and amino acid metabolism to impair cold tolerance in rice.Plant cell reports · 2026Article
- Natural variation in WRKY53 confers cold tolerance at the booting stage between japonica and indica rice.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2026Article
- CRISPR-Cas systems for enhancing chilling tolerance in rice: recent advances and future prospects.Biologia futura · 2026Review
- Identification of CAMTA transcription factors and functional analysis of OsCAMTA4 in rice blast and salt stress.Planta · 2026Article
- Novel HD-Zip transcription factor PCD8 integrates developmental gene networks to shape rice panicle morphogenesis.BMC plant biology · 2026Article
- The Rice Cis-Natural Antisense Transcript NAT1850 of Pri-miR1850 Negatively Regulates Cold Tolerance by Repressing NPR3.Plant biotechnology journal · 2026Article
- Diversification of plant specific organellar single-stranded DNA binding genes and their roles in mitochondrial genome rearrangements in Arabidopsis and rice.BMC plant biology · 2026Article
- Discovery of cold tolerance genes and favorable alleles in Kam sweet rice across various growth stages.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2026Article
- Lower Bolting Height of Winter Rapeseed (Plants (Basel, Switzerland) · 2026Article
- From Shared Mechanisms to Precision Breeding: Engineering Cold and Drought Cross-Tolerance in Crops.International journal of molecular sciences · 2026Review
- Transcriptome Analysis IdentifiesPlants (Basel, Switzerland) · 2026Article
- Article
- Molecular mechanisms of plant freezing tolerance: from cold signal perception to adaptive responses.Frontiers in plant science · 2026Review
- Research progress on cold tolerance key genes and mechanisms in four major northern China crops.Frontiers in plant science · 2026Review
- The OsbZIP35-COR1-OsTCP19 module modulates cell proliferation to regulate grain length and weight in rice.Science advances · 2025Article
- Article
- Rice-specific miR1850.1 targets NPR3 to regulate cold stress response.Plant communications · 2025Article
- Suppressing an auxin efflux transporter enhances rice adaptation to temperate habitats.Nature communications · 2025Article
- Integrating RNA-Seq and linkage mapping to identify and characterizeFrontiers in plant science · 2025Article
- Integrated transcriptome and co-expression network analysis revealed the molecular mechanism of cold tolerance in japonica rice at booting stage.Frontiers in plant science · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
22 authors.
Funding
Abstract
Improvement of cold tolerance at the booting stage (CTB) in rice is a key strategy for cultivation in high-altitude and high-latitude regions. Here, we identify CTB3 gene, encoding a calmodulin-binding transcriptional activator that positively regulates cold tolerance at the booting stage in japonica rice. Two indels (57-bp and 284-bp) in the CTB3 promoter confer a differential transcriptional response to cold between the japonica and indica subspecies. OsTCP19 suppresses CTB3 expression by binding to these indels, negatively regulating cold tolerance. CTB3 activates the expression of TREHALOSE-6-PHOSPHATE PHOSPHATASE1 (OsTPP1), reducing trehalose 6-phosphate (Tre6P) levels, which increases sugar accumulation in panicles and improves cold tolerance. Additionally, favorable alleles of OsTCP19 and CTB3 are selected in japonica rice for cold adaptation. These findings highlight the important role of CTB3 in cold adaptation and its potential for improving cold tolerance in rice breeding.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.