Evidence mapPaperPMID 39950280Full record

ReviewCurrent topics in medicinal chemistry2025

Unveiling the Anticancer Potential of Phytocompounds: Pioneering Future Cancer Therapies.

Prashant Chauhan, Pratibha Pandey, Seema Ramniwas, Meenakshi Verma, Subbulakshmi Ganeshan, Sumit Rajotiya, Seema Devi, Sorabh Lakhanpal, M Ravi Kumar, Shivam Pandey and 1 more

Abstract readReview
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In one paragraph

Review in Current topics in medicinal chemistry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Prashant ChauhanMPA Research, Greater Noida, Uttar Pradesh, India.
Pratibha PandeyCentre for Research Impact and Outcome, Chitkara University Institute of Engineering and Technology, Chitkara University, Rajpura- 140401, Punjab, India.
Seema RamniwasDepartment of Biotechnology, University Centre of Research and Development, Chandigarh University Gharuan, Mohali, Punjab, India.
Meenakshi VermaDepartment of Biotechnology, University Centre of Research and Development, Chandigarh University Gharuan, Mohali, Punjab, India.
Subbulakshmi GaneshanDepartment of Chemistry and Biochemistry, School of Sciences, JAIN [Deemed to be University], Bangalore, Karnataka, India.
Sumit RajotiyaNIMS Institute of Pharmacy, NIMS University, Rajasthan, Jaipur, India.
Seema DeviChandigarh Pharmacy College, Chandigarh group of colleges, Jhanjeri, Mohali 140307, Punjab, India.
Sorabh LakhanpalSchool of Pharmaceutical Sciences, Lovely Professional University, Phagwara, Punjab, India.
M Ravi KumarDepartment of Chemistry, Raghu Engineering College, Visakhapatnam, Andhra Pradesh-531162, India.
Shivam PandeyDepartment of Life Sciences, School of Applied and Life Sciences, Uttaranchal University, Dehradun, India.
Fahad KhanCenter for Global Health Research, Saveetha Medical College and Hospital, Saveetha Institute of medical and Technical Sciences, Chennai, Tamil Nadu, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cancer epidemiological studies highlight the critical need for identifying better treatment options against cancer. Plants have been widely studied to obtain their efficacy as potent therapeutic agents to treat several diseases, including cancer. Interestingly, some phytocompounds, such as flavonoids, terpenoids, alkaloids, phenolics, and organosulphur compounds [OSCs], have been demonstrating their potential role in combating several pathologies, including the second most devasting disease, cancer, which contributes a significant portion of annual mortality cases. Several in vitro, in vivo, and in silico investigations have recently established remarkable properties of phytocompounds such as antioxidant effects, induction of apoptosis, inhibition of metastasis, autophagy modulation, cell cycle regulation, and chemosensitization that lead to cancer suppression. This underscores the great potential of phytocompounds to contribute as an effective anticancerous drug for the prevention of cancer cases and advancement in cancer research. Therefore, comprehending the complicated mechanism involved in the anticancerous effects of phytocompounds against several carcinomas is crucial to establishing novel therapeutic strategies. Thus, this review tends to summarize the involvement of the most promising classes of phytompounds in cancer management and highlights several clinical trial data that demonstrate significant results in managing diverse carcinomas.

Indexed as

Antineoplastic Agents, PhytogenicNeoplasmsPhytochemicalsAnimalsApoptosisCell ProliferationHumansAntineoplastic Agents, PhytogenicPhytochemicalsanticancerapoptosiscancer cellsNatural compoundstherapeutic agents.

Identifiers

PMID39950280

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.