Evidence mapPaperPMID 39950464Full record

ArticleCurrent HIV research2025

Prevalence of Metabolic Syndrome in Iranian Adults Receiving Antiretroviral Treatment for HIV.

Hamid Khazdooz, Ladan Abbasian, Nooshin Shirzad, Pouria Khashayar, SeyedAhmad SeyedAlinaghi, Mahsa Malekahmadi, Mahboobeh Hemmatabadi

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Article in Current HIV research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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7 authors.

Hamid KhazdoozDepartment of Endocrinology, Vali-Asr Hospital, Endocrinology, and Metabolism Research Centre, Imam Khomeini Complex Hospital, Tehran University of Medical Sciences, Tehran, Iran.
Ladan AbbasianDepartment of Infectious Diseases, Iranian Research Center for HIV/AIDS (IRCH), Iranian institute for Reduction of High Risk Behaviors, Imam Khomeini Complex Hospital, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran.
Nooshin ShirzadDepartment of Endocrinology, Vali-Asr Hospital, Endocrinology, and Metabolism Research Centre, Imam Khomeini Complex Hospital, Tehran University of Medical Sciences, Tehran, Iran.
Pouria KhashayarSchool of Life and Medical Sciences, University of Hertfordshire, Hatfield, Hertfordshire, UK.
SeyedAhmad SeyedAlinaghiDepartment of Infectious Diseases, Iranian Research Center for HIV/AIDS (IRCH), Iranian institute for Reduction of High Risk Behaviors, Imam Khomeini Complex Hospital, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran.
Mahsa MalekahmadiDepartment of Clinical Nutrition, School of Nutritional Sciences and Dietetics, Tehran University of Medical Sciences, Tehran, Iran.
Mahboobeh HemmatabadiDepartment of Endocrinology, Vali-Asr Hospital, Endocrinology, and Metabolism Research Centre, Imam Khomeini Complex Hospital, Tehran University of Medical Sciences, Tehran, Iran.

Funding

Tehran University of Medical Sciences, Tehran, Iran 1402-1-119-66384
6 · The paper itself

Abstract

backgroundThe increased risk ofmetabolic syndrome (MetS) and its subcomponents among people living with HIV/AIDS, especially in developing countries, is well documented with the global pooled prevalence of the related risk factors in this population.

objectiveThis study aimed to explore the prevalence of MetS among Iranian People living with HIV according to the ATP III and Iranian criteria.

methodsThe cross-sectional study was conducted on consecutive patients who visited THE referral centre for AIDS/HIV between May to December 2023. A total of 130 participants (n=83; 63.8%male) were investigated based on the inclusion criteria, which included having a minimum age of 25 and a maximum of 65 years and following a stable ART treatment regimen for at least six months. A Chi-square test was used to determine the relationship between the categorical variables. Uni/Multi-variable linear regression analysis was used to quantify the associations between MetS and HIV by the independent variables.

resultsThe incidence of MetS according to ATP III and Iranian criteria were 42 (32.3%) and 45 (34.6%), which was higher in older patients (p=0.001) and those with more duration since HIV diagnosis (p=0.02). Around 33.1% and 16.1% were overweight and obese, respectively. Among the components of MetS, the highest prevalence (50.8%) was related to low HDL, and the lowest was related to fasting blood sugar (21.5%). The average body fat mass, protein mass, Soft lean mass, and percentage body fat were 18.54 ± 9.46 kg, 10.91 ± 2.17 kg, 51.31 ± 9.61 kg, and 24.86±10.25% that were higher in MetS group (p<0.05).

conclusionOur study points out the high prevalence of MetS in an Iranian population living with HIV, especially those suffering from the underlying disease for a longer time. Conducting multi-centric studies with larger sample sizes is needed to confirm our results and determine the most effective measures.

Indexed as

Anti-HIV AgentsHIV InfectionsMetabolic SyndromeAdultAgedCross-Sectional StudiesFemaleHumansIranMaleMiddle AgedPrevalenceRisk FactorsAnti-HIV Agentsabdominal obesity.AIDSHIVMetabolic syndromeobesitywaist circumference

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.