Evidence map›Paper›PMID 39951183›Full record

ArticleVeterinary research communications2025

Evaluation of antibody titer and associated risk factors of goat pox vaccine against lumpy skin disease in crossbred buffaloes.

Adili Abulaiti, Zahid Naseer, Zulfiqar Ahmed, Shijun Tian, Wenju Liu, Muhammad Shoaib, Asghar Khan, Mohamed Abdelrahman, Faisal Ayub Kiani, Abid Hussain and 4 more

Abstract read
In one paragraph

Article in Veterinary research communications, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Adili AbulaitiCollege of Animal Science, Anhui Science and Technology University, Fengyang, Anhui, China. adiliabulaiti@ahstu.edu.cn.
Zahid NaseerFaculty of Veterinary and Animal Sciences, Pir Mehr Ali Shah Arid Agriculture University, Rawalpindi, Pakistan.
Zulfiqar AhmedFaculty of Veterinary and Animal Sciences, University of Poonch Rawalakot, Rawalakot, Azad Jammu and Kashmir, Pakistan.
Shijun TianCollege of Animal Science, Anhui Science and Technology University, Fengyang, Anhui, China.
Wenju LiuCollege of Life and Health Science, Anhui Science and Technology University, Fengyang, Anhui, People's Republic of China.
Muhammad ShoaibFaculty of Veterinary and Animal Sciences, Pir Mehr Ali Shah Arid Agriculture University, Rawalpindi, Pakistan.
Asghar KhanFaculty of Veterinary and Animal Sciences, Pir Mehr Ali Shah Arid Agriculture University, Rawalpindi, Pakistan.
Mohamed AbdelrahmanAnimal Production Department, Faculty of Agriculture, Assuit University, Assuit, Egypt.
Faisal Ayub KianiFaculty of Veterinary and Animal Sciences, Bahauddin Zakariya University, Multan, Pakistan.
Abid HussainFaculty of Veterinary and Animal Sciences, Mirpur University of Science and Technology, Bhimber-Campus, Bhimber, Azad Jammu and Kashmir, Pakistan.
Aftab ShaukatCollege of Veterinary Medicine, South China Agricultural University, Guangzhou, 510642, Guangdong, China.
Umair RiazDepartment of Theriogenology, Faculty of Veterinary and Animal Sciences, The Islamia University of Bahawalpur, Bahawalpur, Pakistan.
Shujuan WangCollege of Animal Science, Anhui Science and Technology University, Fengyang, Anhui, China.
Jinling HuaCollege of Animal Science, Anhui Science and Technology University, Fengyang, Anhui, China. huajl@ahstu.edu.cn.

Funding

Joint Research on Improved Beef Cattle Breeds in Anhui Province [2021]1146Key Research and development program of Anhui Province 202004f06020048Key research and development project of Chuzhou 2018ZN014Natural Science Foundation for Young Scientists of Shanxi Province 31301972Natural Science Foundation of Anhui Province 2008085MC94
6 · The paper itself

Abstract

Lumpy skin disease (LSD) is an infectious disease affecting large ruminants, caused by the lumpy skin disease virus (LSDV). It is characterized by symptoms such as hyperthermia, emaciation, lymphadenopathy, and skin nodules. Pregnant animals affected by LSD often experience abortions and may develop infertility syndrome, while affected males can become sterile. A live attenuated goat pox virus vaccine (GTPV) was administered to various groups of crossbred buffaloes. After vaccination, blood samples were collected from each group to analyze post-vaccination antibody titers. Additionally, vaccinated calves and buffaloes were monitored for growth, body temperature, blood profile, milk production and quality, and reproductive parameters. The study revealed an increase in antibody titer in the weeks following vaccination, with sustained levels for over 150 days before declining by 300 days. During the 7-day observational phase, the vaccinated calves and replacement heifers exhibited significant growth. There were no notable changes in body temperature or milk production in lactating buffaloes within 7 days post-vaccination. However, the buffalo category affected all blood profile indicators significantly (P < 0.05) except for MCHC (P > 0.05) after LSD vaccination. An interaction (P < 0.05) was observed between buffalo categories and days post-exposure for RBCs, HGB, HCT, and MCV values in vaccinated buffaloes. Reproductive parameters, including ovarian resumption, uterine involution rates, and synchronization rate, remained similar in both vaccinated and unvaccinated buffaloes. Overall, the use of the attenuated GTPV vaccine induces a considerable antibody titer without influencing general health or productive parameters, making it a safe and economical method for preventing LSD in buffaloes.

Indexed as

Antibodies, ViralBuffaloesLumpy Skin DiseaseLumpy skin disease virusViral VaccinesAnimalsFemaleMaleRisk FactorsVaccinationVaccines, AttenuatedAntibodies, ViralVaccines, AttenuatedViral VaccinesAntibody titerCrossbred buffaloesLive-attenuated goat pox vaccineLumpy skin diseaseMilk productionReproductive performance

Identifiers

PMID39951183
PMCPMC11828800

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.