Evidence map›Paper›PMID 39953548›Full record

ReviewJournal of translational medicine2025

Role of CD4

Qi An, Li Duan, Yuanyuan Wang, Fuxin Wang, Xiang Liu, Chao Liu, Qinyong Hu

Abstract readReview
In one paragraph

Review in Journal of translational medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. CD4Sensors (Basel, Switzerland) · 2026
    Pooled it
  2. Article
  3. Review
  4. Article
  5. Review
  6. Review
  7. Article
  8. CD4Cancer biology & medicine · 2026
    Review
  9. Article
  10. Article
  11. Article
  12. Article
  13. Review
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Qi An *Department of Oncology, Renmin Hospital of Wuhan University, Wuhan, 430060, China.
Li Duan *Department of Oncology, Renmin Hospital of Wuhan University, Wuhan, 430060, China.
Yuanyuan WangDepartment of Oncology, Renmin Hospital of Wuhan University, Wuhan, 430060, China.
Fuxin WangDepartment of Oncology, Renmin Hospital of Wuhan University, Wuhan, 430060, China.
Xiang LiuDepartment of Radiation Oncology, The Affiliated Cancer Hospital of Gannan Medical University, Jiangxi, 341000, China. aotemanliu1357951@163.com.
Chao LiuDepartment of Radiation Oncology, Peking University First Hospital, Beijing, 100034, China. charles_liu@hsc.pku.edu.cn.ORCID 0000-0002-3807-9901
Qinyong HuDepartment of Oncology, Renmin Hospital of Wuhan University, Wuhan, 430060, China. rm001223@whu.edu.cn.

Funding

Hubei Province Big Health Industry Development Special Fund grant no. 2019916000001National Natural Science Foundation of China grant no. 82403773Postdoctoral Fellowship Program of CPSF 2024M760140Postdoctoral Fellowship Program of CPSF grant no. GZB20230041Shandong Provincial Natural Science Foundation grant no. ZR2021QH006
6 · The paper itself

Abstract

Recent oncological research has intensely focused on the tumor immune microenvironment (TME), particularly the functions of CD4 + T lymphocytes. CD4

Indexed as

CD4-Positive T-LymphocytesImmunityNeoplasmsSingle-Cell AnalysisTumor MicroenvironmentAnimalsHumansSignal TransductionCD4+ T cellsImmunotherapySingle-cell sequencingTumor microenvironment

Identifiers

PMID39953548
PMCPMC11829416

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.