Evidence map›Paper›PMID 39955609›Full record

ArticleBMC research notes2025

Diagnostic value of neutrophil to lymphocyte ratio in identifying gastritis in children with chronic abdominal pain in northern Iran.

Mahbubeh Erfanipour, Mohammadreza Esmaeili Dooki, Hossein-Ali Nikbakht, Hassan Mahmoodi Nesheli, Mohammad Pornasrolah, Maryam Nikpour, Sanaz Mehrabani

Abstract read
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Article in BMC research notes, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Mahbubeh ErfanipourStudent Research Committee, Babol University of Medical Sciences, Babol, Iran.
Mohammadreza Esmaeili DookiPediatric Gastroenterology, Non-Communicable Pediatric Diseases Research Center, Health Research Institute, Babol University of Medical Sciences, Babol, IR, Iran.
Hossein-Ali NikbakhtNon-Communicable Pediatric Diseases Research Center, Health Research Institute, Babol University of Medical Sciences, Babol, IR, Iran.
Hassan Mahmoodi NesheliPediatric Hematology & Oncology, Non-Communicable Pediatric Diseases Research Center, Health Research Institute, Babol University of Medical, Babol, IR, Iran.
Mohammad PornasrolahClinical Research Development Unit of Amirkola Children's Hospital, Babol University of Medical Sciences, Babol, IR, Iran.
Maryam NikpourPhD of Health Science, Non-Communicable Pediatric Diseases Research Center, Health Research Institute, Babol University of Medical Sciences, Babol, IR, Iran.
Sanaz MehrabaniPediatric Gastroenterology, Non-Communicable Pediatric Diseases Research Center, Health Research Institute, Babol University of Medical Sciences, Babol, IR, Iran. mehrabanisanaz@yahoo.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThis study aimed to assess the diagnostic value of the Neutrophil to Lymphocyte Ratio (NLR) specifically for children with suspected gastritis.

methodsThis cross-sectional study included children with chronic abdominal pain referred to Amirkola Children's Hospital, Babol, Iran, in 2021. Gastritis was diagnosed using upper gastrointestinal endoscopy and biopsy, Giemsa staining performed for Helicobacter pylori. Blood samples were analyzed to determine the NLR. Analysis was employed to establish the optimal NLR cut-off for diagnosing gastritis, with sensitivity, specificity, and predictive values calculated.

results126 patients with an average age of 10.03 ± 2.46 were included in this study. 53.2% of children were boys The overall sensitivity and specificity of the mean NLR in diagnosing gastritis in children with abdominal pain based on endoscopy were 11.76% and 97.56%, respectively and for pathology 78.57% and 11.90%, respectively (Area under curve = 0.524 for endoscopy and 0.509 for pathology).

conclusionThis study indicate that the NLR lacks sufficient diagnostic accuracy to serve as a reliable alternative to conventional methods, such as endoscopy and pathology, for diagnosing gastritis or H. Pylori in children with chronic abdominal pain. Standard diagnostic techniques are needed for accurate evaluation and management of Helicobacter pylori-associated gastritis.

Indexed as

Abdominal PainGastritisHelicobacter InfectionsLymphocytesNeutrophilsAdolescentChildChild, PreschoolCross-Sectional StudiesFemaleHelicobacter pyloriHumansIranLymphocyte CountMaleSensitivity and SpecificityChildrenChronic abdominal painGastritisNeutrophil-to-lymphocyte ratio

Identifiers

PMID39955609
PMCPMC11830187

What Socratic holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.