Evidence map›Paper›PMID 39957193›Full record

ReviewJournal of Parkinson's disease2024

Neurotrophic factors for Parkinson's disease: Current status, progress, and remaining questions. Conclusions from a 2023 workshop.

Roger A Barker, Mart Saarma, Clive N Svendsen, Catherine Morgan, Alan Whone, Massimo S Fiandaca, Matthias Luz, Krystof S Bankiewicz, Brian Fiske, Lyndsey Isaacs and 9 more

Abstract readReview
In one paragraph

Review in Journal of Parkinson's disease, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. Article
  3. Clinical GDNF delivery methods for Parkinson's disease.Journal of Parkinson's disease · 2026
    Review
  4. Review
  5. Review
  6. Pharmacogenetics in advanced Parkinson's disease.Journal of neural transmission (Vienna, Austria : 1996) · 2025
    Review
  7. Review
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors.

Roger A BarkerDepartment of Clinical Neurosciences and Cambridge Stem Cell Institute, John van Geest Centre for Brain Repair, Forvie Site, Cambridge, UK.ORCID 0000-0001-8843-7730
Mart SaarmaInstitute of Biotechnology, HiLIFE, University of Helsinki, Helsinki, Finland.
Clive N SvendsenBoard of Governors Regenerative Medicine Institute, Cedars-Sinai Medical Center, Los Angeles, CA, USA.
Catherine MorganMovement Disorders Group, Bristol Brain Centre, North Bristol NHS Trust, Southmead Hospital, Southmead Road, Bristol, UK.ORCID 0000-0003-0333-2417
Alan WhoneMovement Disorders Group, Bristol Brain Centre, North Bristol NHS Trust, Southmead Hospital, Southmead Road, Bristol, UK.
Massimo S FiandacaAsklepios BioPharmaceutical, Inc. (AskBio), Research Triangle Park, NC, USA.ORCID 0000-0002-8376-1934
Matthias LuzAsklepios BioPharmaceutical, Inc. (AskBio), Research Triangle Park, NC, USA.ORCID 0000-0001-6646-3655
Krystof S BankiewiczAsklepios BioPharmaceutical, Inc. (AskBio), Research Triangle Park, NC, USA.
Brian FiskeThe Michael J Fox Foundation for Parkinson's Research, Grand Central Station, New York, NY, USA.
Lyndsey IsaacsCure Parkinson's, London, UK.
Arthur RoachParkinson's, London, UK.
Thomas PhippsParkinson's research advocate, UK.
Jeffrey H KordowerASU-Banner Neurodegenerative Disease Research Center, Arizona State University, Tempe, AZ, USA.
Emma L LaneSchool of Pharmacy and Pharmaceutical Sciences, Cardiff University, Cardiff, UK.ORCID 0000-0001-8800-3764
Henri J HuttunenHerantis Pharma Plc, Espoo, Finland.
Aideen SullivanDepartment of Pharmacology and Therapeutics, School of Medicine, University College Cork, Cork, Ireland.ORCID 0000-0001-9692-6438
Gerard O'KeeffeDepartment of Anatomy and Neuroscience, School of Medicine, University College Cork, Cork, Ireland.ORCID 0000-0001-5149-0933
Valeria YartsevaKenai Therapeutics, San Diego, CA, USA.
Howard FederoffKenai Therapeutics, San Diego, CA, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In 2023, a workshop was organized by the UK charity Cure Parkinson's with The Michael J Fox Foundation for Parkinson's Research and Parkinson's UK to review the field of growth factors (GFs) for Parkinson's disease (PD). This was a follow up to a previous meeting held in 2019.

Indexed as

Nerve Growth FactorsParkinson DiseaseHumansNerve Growth Factorsanimal modelsend pointsGDNFgene therapyParkinson'spatient voicetrialsworkshop

Identifiers

PMID39957193
PMCPMC13348327

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.