Evidence map›Paper›PMID 39957613›Full record

ReviewCirculation. Cardiovascular imaging2025

Imaging of the Acute and Chronic Cardiovascular Complications of Radiation Therapy.

James Wilson, Chong Jun Hua, Nikoo Aziminia, Charlotte Manisty

Abstract readReview
In one paragraph

Review in Circulation. Cardiovascular imaging, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
  4. Article
  5. Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

James WilsonBarts Heart Centre, St Bartholomew's Hospital, Barts Health National Health Service (NHS) Trust, London, United Kingdom (J.W., N.A., C.M.).ORCID 0000-0002-7837-5625
Chong Jun HuaCardiology Department, National Heart Centre Singapore & Cardiovascular Sciences Academic Clinical Programme at Duke-National University of Singapore Medical School & Lee Kong Chian School of Medicine, Nanyang Technological University (C.J.H.).
Nikoo AziminiaBarts Heart Centre, St Bartholomew's Hospital, Barts Health National Health Service (NHS) Trust, London, United Kingdom (J.W., N.A., C.M.).ORCID 0000-0001-5333-1194
Charlotte ManistyBarts Heart Centre, St Bartholomew's Hospital, Barts Health National Health Service (NHS) Trust, London, United Kingdom (J.W., N.A., C.M.).ORCID 0000-0003-0245-7090

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Chest radiotherapy (XRT) plays a crucial role in the treatment of a multitude of cancers including breast, lung, esophageal, and lymphoma. Although XRT enhances cancer survival rates, it may also expose healthy bystander tissues to radiation, potentially leading to severe complications. Initially considered relatively resistant to radiation damage, the heart has been shown over the past 4 decades to be susceptible to radiation-induced cardiovascular toxicity and despite advances in XRT which can minimize radiation exposure to heart tissue, no cardiac radiation dose is entirely safe. The clinical spectrum of radiation-induced cardiovascular toxicity is broad, encompassing coronary artery disease, myocardial dysfunction, valvular abnormalities, and pericardial disorders. Radiation-induced cardiovascular toxicity may manifest acutely or many years after XRT, with each condition more likely to present at certain time points post-XRT. Cardiac imaging is a crucial tool in both the screening and diagnosis of radiation-induced cardiovascular toxicity with an understanding of its pathophysiology, incidence, and progression required to implement a comprehensive, multimodality imaging approach to detect and manage these complications effectively.

Indexed as

Cardiac Imaging TechniquesCardiovascular DiseasesNeoplasmsRadiation InjuriesRadiotherapyAcute DiseaseCardiotoxicityChronic DiseaseHumansPredictive Value of TestsRisk Factorscardioonclogy coronary artery diseaseechocardiographyheart failuremagnetic resonance imagingradiation therapy

Identifiers

PMID39957613
PMCPMC11913245

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.