Evidence map›Paper›PMID 39960871›Full record

ArticleThe journal of physical chemistry. B2025

Coupled Heterogeneity to Dimeric Site-Specific Binding by the POU-Family Transcription Factor OCT2.

J Ross Terrell, Gregory M K Poon

Abstract read
In one paragraph

Article in The journal of physical chemistry. B, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

J Ross TerrellDepartment of Chemistry, Georgia State University, Atlanta, Georgia 30303, United States.
Gregory M K PoonDepartment of Chemistry, Georgia State University, Atlanta, Georgia 30303, United States.ORCID 0000-0001-5107-9458

Funding

Direct chemical control of the hematopoietic master transcription factor PU.1R01HL155178 · NHLBI · GEORGIA STATE UNIVERSITY · PI POON, GREGORY MAN KAI · 2021 to 2023
$1.2M
Profiling the specificity of SPI1 and SPIB activity for drug discoveryR03TR004842 · NCATS · GEORGIA STATE UNIVERSITY · PI POON, GREGORY MAN KAI · 2025 to 2025
$156k
NCATS NIH HHS R03 TR004842NHLBI NIH HHS R01 HL155178
6 · The paper itself

Abstract

POU-family transcription factors regulate metazoan gene expression via a bipartite DNA-binding domain consisting of two covalently linked helix-turn-helix subdomains, POU

Indexed as

DNABinding SitesCrystallography, X-RayModels, MolecularMolecular Dynamics SimulationProtein BindingProtein MultimerizationThermodynamicsDNA

Identifiers

PMID39960871
PMCPMC11873960

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.