ArticleNature2025
Characterization of single neurons reprogrammed by pancreatic cancer.
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Article in Nature, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 71 papers.
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71citing papers in PubMed
–field-weighted citation impact
What it found
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
71 citing papers in PubMed.
- The next 25 years of cancer research: emerging perspectives and priorities.Nature reviews. Cancer · 2026Article
- Mechanisms of neuropeptide-mediated immune sensing in the modulation of antitumor immunity.Journal for immunotherapy of cancer · 2026Review
- Trace-n-Seq combines retrograde fluorescent tracing with sorting and single-cell sequencing of innervating peripheral neurons.Nature protocols · 2026Review
- Decoding neuro-tumor interactions in pancreatic cancer: mechanisms, immunosuppressive networks and therapeutic opportunities.Molecular biomedicine · 2026Review
- Targeting the nervous system: Mechanistic insights into neuro-tumor communication and therapeutic opportunities.Acta pharmaceutica Sinica. B · 2026Review
- Neuron-Associated Transcriptional Enrichment Is Associated with Distinct Biological States and Predicts Poor Prognosis in Gastric Cancer.Annals of surgical oncology · 2026Article
- Decoding age-stratified clinical and molecular heterogeneity in male breast cancer through multiomic profiling.Chinese journal of cancer research = Chung-kuo yen cheng yen chiu · 2026Article
- Neuro-immune crosstalk in lung cancer brain metastasis: mechanisms, therapeutic targets, and translational opportunities.Medical oncology (Northwood, London, England) · 2026Review
- The tumor microenvironment in pancreatic cancer: from composition to therapeutic targeting.Biochemical Society transactions · 2026Review
- A Candidate Small Molecule Targeting Tachykinin Receptor 1 Suppresses Substance P‑Driven Extracellular Signal-Regulated Kinase Activation and Tumor Innervation in Pancreatic Cancer.ACS pharmacology & translational science · 2026Article
- Association of tumor Schwann cells with epithelial-mesenchymal transition and immune-suppressive microenvironment in triple-negative breast cancer.Breast cancer research and treatment · 2026Article
- ASO Author Reflections: Neuron Projection Guidance-A transcriptomic perspective on tumor-induced neural recruitment in breast cancer.Annals of surgical oncology · 2026Article
- Article
- Pancreatic cancer cachexia promotes cardiac dysfunction through altered adrenergic signalling in the heart.The Journal of physiology · 2026Article
- Neural regulation of tumor immunity: emerging opportunities to enhance cancer immunotherapy.Experimental & molecular medicine · 2026Review
- MTA2: Decoding pathogenic mechanisms, clinical implications and therapeutic frontiers across disease landscapes (Review).International journal of molecular medicine · 2026Review
- A Neuron Projection Guidance Signature Associates with Immune-Cold Tumor Microenvironment and Poor Outcomes in Breast Cancer.Annals of surgical oncology · 2026Article
- Discovery of a peripherally restricted αCell reports. Medicine · 2026Article
- The lethal symbiont: exploring the pathophysiology of cancer.Physiological reviews · 2026Review
- KRAS/ACTN4/p65-NR2A axis mediates glutamine-glutamate metabolic coupling between schwann cells and pancreatic cancer promoting perineural invasion.Journal of advanced research · 2026Article
11 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
26 authors.
Vera Thiel *Heidelberg Institute for Stem Cell Technology and Experimental Medicine (HI-STEM), Heidelberg, Germany.
Simon Renders *Heidelberg Institute for Stem Cell Technology and Experimental Medicine (HI-STEM), Heidelberg, Germany.
Jasper Panten *Heidelberg Institute for Stem Cell Technology and Experimental Medicine (HI-STEM), Heidelberg, Germany.
Nicolas DrossNikon Imaging Center, University of Heidelberg, Heidelberg, Germany.
Katharina BauerSingle-cell Open Lab, DKFZ, Heidelberg, Germany.
Daniel AzorinFaculty of Biosciences, Heidelberg University, Heidelberg, Germany.
Vanessa HenriquesDepartment of Pathology, Heidelberg University Hospital, Heidelberg, Germany.
Vanessa VogelHeidelberg Institute for Stem Cell Technology and Experimental Medicine (HI-STEM), Heidelberg, Germany.
Corinna KleinHeidelberg Institute for Stem Cell Technology and Experimental Medicine (HI-STEM), Heidelberg, Germany.
Aino-Maija LeppäHeidelberg Institute for Stem Cell Technology and Experimental Medicine (HI-STEM), Heidelberg, Germany.
Isabel Barriuso OrtegaFaculty of Biosciences, Heidelberg University, Heidelberg, Germany.ORCID 0000-0003-1351-5575
Jonas SchwickertHeidelberg Institute for Stem Cell Technology and Experimental Medicine (HI-STEM), Heidelberg, Germany.
Iordanis OurailidisDepartment of Pathology, Heidelberg University Hospital, Heidelberg, Germany.ORCID 0000-0001-6783-5617
Julian MochayediFaculty of Biosciences, Heidelberg University, Heidelberg, Germany.
Jan-Philipp MallmSingle-cell Open Lab, DKFZ, Heidelberg, Germany.
Carsten Müller-TidowDepartment of Internal Medicine V, Hematology, Oncology and Rheumatology, Heidelberg University Hospital, Heidelberg, Germany.ORCID 0000-0002-7166-5232
Hannah MonyerGerman Cancer Research Center (DKFZ), Heidelberg, Germany.ORCID 0000-0002-9332-5749
John NeoptolemosDepartment of General, Visceral and Transplantation Surgery, Heidelberg University Hospital, Heidelberg, Germany.ORCID 0000-0002-6201-7399
Thilo HackertDepartment of General, Visceral and Transplantation Surgery, Heidelberg University Hospital, Heidelberg, Germany.ORCID 0000-0002-7012-1196
Oliver StegleGerman Cancer Research Center (DKFZ), Heidelberg, Germany.ORCID 0000-0002-8818-7193
Duncan T OdomGerman Cancer Research Center (DKFZ), Heidelberg, Germany.ORCID 0000-0001-6201-5599
Rienk OffringaGerman Cancer Research Center (DKFZ), Heidelberg, Germany.
Albrecht StenzingerDepartment of Pathology, Heidelberg University Hospital, Heidelberg, Germany.ORCID 0000-0003-1001-103X
Frank WinklerGerman Cancer Research Center (DKFZ), Heidelberg, Germany.ORCID 0000-0003-4892-6104
Martin SprickHeidelberg Institute for Stem Cell Technology and Experimental Medicine (HI-STEM), Heidelberg, Germany.ORCID 0000-0001-9691-7574
Andreas TrumppHeidelberg Institute for Stem Cell Technology and Experimental Medicine (HI-STEM), Heidelberg, Germany. a.trumpp@dkfz-heidelberg.de.ORCID 0000-0002-6212-3466
Funding
No grant is acknowledged in the PubMed record.
Abstract
The peripheral nervous system (PNS) orchestrates organ function in health and disease. Most cancers, including pancreatic ductal adenocarcinoma (PDAC), are infiltrated by PNS neurons, and this contributes to the complex tumour microenvironment (TME)
Indexed as
Carcinoma, Pancreatic DuctalCellular ReprogrammingNeuronsPancreatic NeoplasmsSingle-Cell AnalysisAnimalsAxonsFemaleHumansMaleMicePaclitaxelPancreasPancreatitisSensory Receptor CellsTranscriptomePaclitaxel
Identifiers
What Socratic holds
Textmetadata
LicenceCC BY
Read underepoch 390
Registered trials
None linked
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.