Evidence map›Paper›PMID 39962033›Full record

ArticleProbiotics and antimicrobial proteins2025

Promising Antidepressant Potential: The Role of Lactobacillus rhamnosus GG in Mental Health and Stress Response.

Musab Işık, Fadime Köse, Cansu Özbayer, Özcan Budak, Rumeysa Keleş Kaya, Derya Güzel Erdoğan, Mehmet Arif Demirci, Songül Doğanay, Cahit Bağcı

Abstract read
In one paragraph

Article in Probiotics and antimicrobial proteins, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Review
  2. The Combination ofNutrients · 2026
    Article
  3. Review
  4. Review
  5. Review
  6. Understanding the diversity and roles of the canine gut microbiome.Journal of animal science and biotechnology · 2025
    Review
  7. Article
  8. Frontiers in microbiology · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Musab Işıkİstanbul Aydın University, Istanbul, Turkey. musab_adp@hotmail.com.ORCID http://orcid.org/0000-0002-1116-337X
Fadime KöseSakarya University, Adapazarı, Adapazarı, Turkey.ORCID http://orcid.org/0000-0002-6822-6263
Cansu ÖzbayerKutahya Saglik Bilimleri Universitesi, Kütahya, Turkey.ORCID http://orcid.org/0000-0002-1120-1874
Özcan BudakSakarya University, Adapazarı, Adapazarı, Turkey.ORCID http://orcid.org/0000-0002-2617-3175
Rumeysa Keleş KayaSağlık Bilimleri Üniversitesi, Istanbul, Turkey.ORCID http://orcid.org/0000-0002-5554-1918
Derya Güzel ErdoğanSakarya University, Adapazarı, Adapazarı, Turkey.ORCID http://orcid.org/0000-0002-7618-5043
Mehmet Arif DemirciMuş Alparslan University, Muş, Turkey.ORCID http://orcid.org/0000-0003-2679-6281
Songül DoğanaySakarya University, Adapazarı, Adapazarı, Turkey.ORCID http://orcid.org/0000-0002-1730-1331
Cahit BağcıSakarya University, Adapazarı, Adapazarı, Turkey.ORCID http://orcid.org/0000-0001-5211-4366

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Chronic stress is linked to changes in brain physiology and functioning, affects the central nervous system (CNS), and causes psychiatric diseases such as depression and anxiety. In this study, antidepressant effects of the probiotic bacterium Lactobacillus rhamnosus GG (ATCC 53103) (LGG) (15 × 10

Indexed as

Antidepressive AgentsDepressionLacticaseibacillus rhamnosusProbioticsStress, PsychologicalAnimalsBehavior, AnimalBrain-Derived Neurotrophic FactorMaleMental HealthRatsRats, WistarVenlafaxine HydrochlorideAntidepressive AgentsBrain-Derived Neurotrophic FactorVenlafaxine Hydrochloride

Identifiers

PMID39962033
PMCPMC12634810

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.