Evidence mapPaperPMID 39962072Full record

ArticleScientific reports2025

Management of cardiovascular disease by cerium oxide nanoparticles via alleviating oxidative stress and adipokine abnormalities.

Samir A E Bashandy, Marawan A Elbaset, Fatma A A Ibrahim, Sahar S Abdelrahman, Sherif A Abdelmottaleb Moussa, Ahmed M A El-Seidy

Abstract read
In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Article
  3. The Protective Effect of N, Ce-doped Carbon Dots Against HApplied biochemistry and biotechnology · 2026
    Article
  4. Article
  5. Review
  6. Review
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Samir A E BashandyPharmacology Department, Medical Research and Clinical Studies Institute, National Research Centre, El-bohouth St., P.O. 12622, Dokki, Cairo, Egypt.
Marawan A ElbasetPharmacology Department, Medical Research and Clinical Studies Institute, National Research Centre, El-bohouth St., P.O. 12622, Dokki, Cairo, Egypt. dr.marawan@gmail.com.
Fatma A A IbrahimDepartment of Biochemistry, Biotechnology Research Institute, National Research Centre, El-bohouth St., P.O. 12622, Dokki, Cairo, Egypt.
Sahar S AbdelrahmanPathology Department, Faculty of Veterinary Medicine, Cairo University, Giza, Egypt.
Sherif A Abdelmottaleb MoussaDepartment of Biochemistry, Biotechnology Research Institute, National Research Centre, El-bohouth St., P.O. 12622, Dokki, Cairo, Egypt.
Ahmed M A El-SeidyInorganic Chemistry Department, Advanced Materials Technology & Mineral Resources Research Institute, National Research Centre, El-bohouth St., P.O. 12622, Dokki, Cairo, Egypt. am.elseidy@nrc.sci.eg.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The current study aimed to evaluate the role of cerium oxide nanoparticles (C-1), a potent antioxidant, in the medication of cardiovascular disease in obese animal model. C-1 was prepared using a modified sonication sol-gel method. Thirty-two adult male rats were equally divided into 4 groups (n=8/each). The first (control) and second (obese) groups are not treated while the obese rats in the third and fourth groups were given 15 and 30 mg/kg C-1(IP), respectively, for 8 weeks. Parameters of insulin resistance, adipocyte hormones, inflammatory markers, lipid profile, cardiac enzymes and cardiac iron content (C-Fe) were estimated. Moreover, histological study and immunohistochemical stain for inducible nitric oxide synthase (INOS) for cardiac and aortic tissues were performed. The XRD patterns of C-1 showed narrow symmetric diffraction peaks. The particle diameters were calculated from the TEM histogram (21.09 nm) and the Debye-Scherrer Method (20.74 nm) which were very similar. Using the most intense peak (

Indexed as

AdipokinesCardiovascular DiseasesCeriumNanoparticlesOxidative StressAnimalsAntioxidantsDisease Models, AnimalInsulin ResistanceMaleMyocardiumObesityRatsAdipokinesAntioxidantsceric oxideCeriumAdipokinesAortaCardiac muscleCerium oxide nanoparticlesInsulin resistanceObesityOxidative stress

Identifiers

PMID39962072
PMCPMC11833101

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.