Evidence map›Paper›PMID 39962437›Full record

ArticleBMC pregnancy and childbirth2025

Obsessive-compulsive disorder (OCD) symptoms during pregnancy and postpartum: prevalence, stability, predictors, and comorbidity with peripartum depression symptoms.

Sandra Nakić Radoš, Maja Brekalo, Marijana Matijaš, Maja Žutić

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Article in BMC pregnancy and childbirth, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

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0cells of the map it votes in
6citing papers in PubMed
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1 · What the graph read from it

What it found

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2 · The registry

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3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

4 authors.

Sandra Nakić RadošDepartment of Psychology, Catholic University of Croatia, Ilica 244, Zagreb, 10000, Croatia. snrados@unicath.hr.ORCID http://orcid.org/0000-0002-8330-8427
Maja BrekaloDepartment of Psychology, Catholic University of Croatia, Ilica 244, Zagreb, 10000, Croatia.
Marijana MatijašDepartment of Psychology, Catholic University of Croatia, Ilica 244, Zagreb, 10000, Croatia.
Maja ŽutićDepartment of Psychology, Catholic University of Croatia, Ilica 244, Zagreb, 10000, Croatia.

Funding

Hrvatska Zaklada za Znanost DOK-2020-01-4127Hrvatska Zaklada za Znanost HRZZ-MOBODL-2023-12-6514Hrvatsko Katoličko Sveučilište MumHealth
6 · The paper itself

Abstract

backgroundPregnancy and postpartum are considered vulnerable periods for new parents to develop obsessive-compulsive disorder (OCD). The aim of this study was threefold: (1) to establish the prevalence of OCD symptoms and its course in the peripartum period; (2) to examine comorbidity with depressive symptoms; and (3) to investigate which sociodemographic, obstetric, and individual characteristics are predictors of OCD symptoms.

methodsA longitudinal study included 397 women during pregnancy (T1) and 6-12 weeks postpartum (T2). Participants filled out the obstetrical and demographic sheet, Anxiety Sensitivity Index (ASI), Emotional Stability subscale from the International Personality Item Pool-50 (IPIP-50), Brief Resilience Scale (BRS) all at T1, and Yale-Brown Obsessive Compulsive Scale (Y-BOCS) and Edinburgh Postpartum Depression Scale (EPDS) at T1 and T2.

resultsIn this sample, 15.1% of women reported OCD symptoms during pregnancy and 15.1% in the postpartum, with 9.8% of women who had symptoms at both time points. However, the majority of women experienced symptoms of mild severity, according to the Y-BOCS. Of the women experiencing OCD symptoms, 33% and 43% had comorbid depressive symptoms in pregnancy and the postpartum period, respectively. The level of OCD symptoms significantly decreased after childbirth. None of the sociodemographic or obstetric variables were a significant predictor of OCD symptoms during pregnancy or postpartum. After controlling for current depression symptoms, higher psychological concerns of anxiety sensitivity (but not physical and social concerns) and higher neuroticism were significant predictors of higher levels of OCD symptoms both at T1 and T2. At the same time, higher resilience was a significant predictor of lower levels of OCD symptoms only at T1.

conclusionOne in six women has OCD symptoms in the peripartum period, with substantial comorbidity with depression symptoms. Women who are high on neuroticism and anxiety sensitivity are prone to OCD symptoms, while resilience is a significant protective factor. CLINICAL TRIAL NUMBER: Not applicable.

Indexed as

DepressionDepression, PostpartumObsessive-Compulsive DisorderPeripartum PeriodPostpartum PeriodPregnancy ComplicationsAdultComorbidityFemaleHumansLongitudinal StudiesPregnancyPrevalencePsychiatric Status Rating ScalesYoung AdultComorbidityDepressionObsessive-compulsive disorderPostpartumPregnancy

Identifiers

PMID39962437
PMCPMC11834599

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.