Evidence map›Paper›PMID 39962906›Full record

ArticleOral diseases2025

Differences in Oral Squamous Cell Carcinoma From Colombia and Spain: A Retrospective Cohort Study.

Ana María Rochel-Rochel, Julio Acero-Sanz, Juan Carlos de Vicente, Vito Carlo Alberto Caponio, Cristina Cárdenas-Serres, Catalina Cáceres Ramírez, Silvia Juliana Villabona Flórez, Viviana Jiménez Andrade, Diego Gómez Abreu, Francy Archilla Flórez and 1 more

Abstract readComparative Study
In one paragraph

Article in Oral diseases, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Ana María Rochel-RochelDepartment of Dental Clinical Specialties, Faculty of Dentistry, Complutense University, Madrid, Spain.
Julio Acero-SanzDepartment of Oral and Maxillofacial Surgery, Hospital Universitario Ramón Y Cajal, University of Alcala, IRYCIS, Madrid, Spain.
Juan Carlos de VicenteORALMED Research Group, Department of Dental Clinical Specialties, School of Dentistry, Complutense University, Madrid, Spain.ORCID https://orcid.org/0000-0002-0991-9465
Vito Carlo Alberto CaponioORALMED Research Group, Department of Dental Clinical Specialties, School of Dentistry, Complutense University, Madrid, Spain.ORCID https://orcid.org/0000-0001-5080-5921
Cristina Cárdenas-SerresDepartment of Oral and Maxillofacial Surgery, Hospital Universitario Ramón Y Cajal, Madrid, Spain.
Catalina Cáceres RamírezFOSCAL Research Division, FOSCAL Clinic, Floridablanca, Colombia.
Silvia Juliana Villabona FlórezFOSCAL Research Division, FOSCAL Clinic, Floridablanca, Colombia.
Viviana Jiménez AndradeUniversidad De La Sabana, Bogotá, Colombia.
Diego Gómez AbreuInternational Hospital in Colombia, HIC, Piedecuesta, Colombia.
Francy Archilla FlórezErasmo Meoz University Hospital, Cúcuta, Colombia.
Rosa María López-PintorDepartment of Dental Clinical Specialties, Faculty of Dentistry, Complutense University, Madrid, Spain.ORCID https://orcid.org/0000-0002-5727-0920

Funding

Instituto de Salud Carlos IIIMinisterio de Ciencia Tecnología e Innovaciónthe European Union-Next Generation EU through the Italian Ministry of University and Research under PNRR - M4C2-I1.3 Project PE_00000019 "HEAL ITALIA HEALTH EXTENDED ALLIANCE FOR INNOVATIVE THERAPIES, ADVANCED LAB-RESEARCH, AND INTEGRATED APPROACHES OF PRECISION MEDICINE" to Vito Carlo Alberto Caponio, CUPD73C22001230006
6 · The paper itself

Abstract

objectiveTo compare the clinicopathological characteristics and survival of two cohorts of patients with oral squamous cell carcinoma (OSCC) from Spain and Colombia.

methodsClinicopathological and survival variables of patients with OSCC from six maxillofacial surgery departments in Spain and Colombia were retrospectively reviewed. Variables were compared according to country of origin.

resultsWe included 649 patients, 359 from Spain and 290 from Colombia. The Colombian cohort was younger, drank more alcohol, had less comorbidities, and reported a greater mean number of days both from symptoms to diagnosis and from then to treatment, which was ∼2.5 times longer in the Colombian cohort. Colombian patients were diagnosed at a more advanced stage. The treatment of choice was resective surgery. In the Colombian cohort, more patients received radio and chemotherapy together with surgery. Second primary tumors and recurrences were more frequent in the Colombian sample (7.2% vs. 2.8%; p = 0.008) and in the Spanish cohort (32% vs. 23.1%; p = 0.012), respectively. Overall survival was similar between the two samples (HR = 1.15; 95% CI = 0.93-1.42; p = 0.195) and disease-specific survival was worse in the Colombian one (HR = 1.30; 95% CI = 1.03-1.65; p = 0.027).

conclusionsThere were epidemiological differences between patients with OSCC in both cohorts and a longer delay in diagnosis and treatment in the Colombian sample.

Indexed as

Carcinoma, Squamous CellMouth NeoplasmsAdultAgedAged, 80 and overColombiaFemaleHumansMaleMiddle AgedNeoplasm Recurrence, LocalRetrospective StudiesSpaindelayed diagnosishealthcare systemmouth neoplasmsoral squamous cell carcinomaprognostic factorsrisk factorssurvival rate

Identifiers

PMID39962906
PMCPMC12291432

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.