ArticleNeuropsychiatric disease and treatment2025
The Effects of Hyperlipidemia on Postoperative Cognitive Dysfunction in Patients Undergoing Laparoscopic Gynecological Tumor Surgery.
Article in Neuropsychiatric disease and treatment, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
3 citing papers in PubMed.
- Development and validation of a LASSO-derived prognostic model predicting postoperative cognitive dysfunction risk in off-pump coronary artery bypass grafting patients.Journal of thoracic disease · 2026Article
- Metabolic syndrome and perioperative neurocognitive disorders: epidemiology, mechanisms, and interventions.Frontiers in neuroscience · 2026Review
- Low serum triglycerides related to delayed neurocognitive recovery in geriatric oral and maxillofacial surgery patients: A prospective cohort study.Lipids in health and disease · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: POCD is a common postoperative complication associated with anesthesia and surgery. Its occurrence reduces the quality of life after surgery and increases the risk of death and disability. Related studies demonstrated that hyperlipidemia could affect the occurrence and development of patients' cognitive dysfunction. However, the association between hyperlipidemia and POCD has not been well examined. Methods: A total of 98 patients were divided into hyperlipidemia group and normal lipid group based on blood lipid level. Minimum Mental State Examination was used to evaluate the preoperative cognitive status. The patients were assessed with the Montreal Cognitive Assessment 1 day before operation and 7 days after operation. The Telephone Interview for Cognitive Status-Modified was applied to evaluate the cognitive ability 1 and 3 months after surgery. We analyzed the incidence of POCD and its potential risk factors according to the scores on each scale after operation. Results: A total of 98 patients including 52 patients in the hyperlipidemia group and 46 patients in the normal blood lipid group completed all postoperative follow-up. POCD occurred in 27 patients 7 days after surgery, including 19 patients (36.54%) in the hyperlipidemia group and 8 patients (17.39%) in the normal group. One month after surgery, 23 patients experienced POCD, with 17 (32.69%) in the hyperlipidemia group and 6 (13.04%) in the normal group. And three months after surgery, 20 patients experienced POCD, including 14 (26.92%) in the hyperlipidemia group and 6 (13.04%) in the normal group. Through univariate and multivariate regression analysis, we found that age and total cholesterol level were significantly associated with the occurrence of POCD. Conclusion: Preoperative hyperlipidemia was associated with the occurrence of POCD 7 days and 1 month after laparoscopic gynecologic tumor surgery. Age and preoperative hypercholesterolemia were considered independent risk factors for POCD development.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.