Evidence map›Paper›PMID 39963238›Full record

ReviewFrontiers in pharmacology2025

Bioprinted hydrogels in bone regeneration: a bibliometric analysis.

Huijie Zhang, Xiaoyu Li, Zhenyu Jia, Kun Jiao, Chen Liu, Zixiang Deng, Yushu Bai, Xianzhao Wei, Xiaoyi Zhou

Abstract readReview
In one paragraph

Review in Frontiers in pharmacology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Huijie Zhang *Department of Orthopedics, Shanghai Changhai Hospital, Shanghai, China.
Xiaoyu Li *Department of Orthopedics, Shanghai Changhai Hospital, Shanghai, China.
Zhenyu Jia *Department of Orthopedics, General Hospital of Southern Theater Command, Guangzhou, China.
Kun JiaoDepartment of Orthopedics, Shanghai Changhai Hospital, Shanghai, China.
Chen LiuDepartment of Orthopedics, Shanghai Changhai Hospital, Shanghai, China.
Zixiang DengDepartment of Orthopedics, Shanghai Changhai Hospital, Shanghai, China.
Yushu BaiDepartment of Orthopedics, Shanghai Changhai Hospital, Shanghai, China.
Xianzhao WeiDepartment of Orthopedics, Shanghai Changhai Hospital, Shanghai, China.
Xiaoyi ZhouDepartment of Orthopedics, Shanghai Changhai Hospital, Shanghai, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: The application of bioprinted hydrogels in the field of bone regeneration is garnering increasing attention. The objective of this study is to provide a comprehensive overview of the current research status, hotspots and research directions in this field through bibliometric methods, and to predict the development trend of this field. Methods: A search was conducted on 27 December 2024, for papers published on the Web of Science from 2010 to 2025. We used the bibliometrix package in the software program R to analyze the retrieved data and VOSviewer and CiteSpace to visualize hotspots and research trends in bioprinted hydrogels for bone regeneration. Results: We identified and reviewed 684 articles published in this field between 2010 and 2025. A total of 811 institutions and 1,166 researchers from 41 countries/regions contributed to these publications. Among them, China led in terms of the number of articles published, single-country publications (SCP), and multi-country publications (MCP). Our bibliometric-based visualization analysis revealed that the mechanical properties and osteogenic differentiation capacity of biomaterials have been a focal research topic over the past decade, while emerging research has also concentrated on the Conclusion: This study provides an in-depth analysis of the research trajectory in the application of bioprinted hydrogels for bone regeneration. The number of research papers in this field is increasing annually, and the main research hotspots include bone regeneration, 3D printing, scaffolds, and hydrogels. Future research directions may focus on gelatin, additive manufacturing, and growth factors. Additionally, international collaboration is essential to enhance the effectiveness of bioprinted hydrogels in bone regeneration applications.

Indexed as

bibliometricbioprintingbone regenerationhydrogeltissue engineering

Identifiers

PMID39963238
PMCPMC11830744

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.