ArticleMagnetic resonance in medicine2025
Whole-brain BOLD responses to graded hypoxic challenges at 7 T, 9.4 T, and 15.2 T: Implications for ultrahigh-field functional and dynamic susceptibility contrast MRI.
Article in Magnetic resonance in medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
What it found
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Who cites it
4 citing papers in PubMed.
- Molecular changes in hypoxia-induced central neural circuits and nuclei.Medical gas research · 2026Review
- Hypoxia-targeted BOLD MRI signal heterogeneity as a complementary metric for glioblastoma characterization: a pilot study.Journal of neuro-oncology · 2026Article
- Whole-brain BOLD responses to graded hypoxic challenges at 7 T, 9.4 T, and 15.2 T: Implications for ultrahigh-field functional and dynamic susceptibility contrast MRI.Magnetic resonance in medicine · 2025Article
- Review
Corrections and comments
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Authors and funding
9 authors.
Funding
Abstract
purposeBlood oxygen-level dependent (BOLD) functional MRI signals depend on changes in deoxyhemoglobin content, which is associated with baseline cerebral blood volume (CBV) and blood oxygen saturation change. To accurately interpret activation-induced BOLD responses and quantify perfusion values by BOLD dynamic susceptibility contrast (BOLD-DSC) with transient hypoxia, it is critical to assess Δ
methodsWhole-brain BOLD responses were examined using 5-s graded hypoxic challenges with 10%, 5%, and 0% O
resultsSubstantial heterogeneity in hypoxia-induced Δ
conclusionsOur investigations provide biophysical insights into the BOLD contrast mechanism at ultrahigh fields, and address quantification issues in susceptibility-based CBV measurements.
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Registered trials
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