Evidence map›Paper›PMID 39964627›Full record

ArticleAging clinical and experimental research2025

Clinical implication of anemia in older patients with dementia with lewy bodies.

Abdulkadir Karismaz, Pinar Soysal, Rafet Eren, Istemi Serin, Irem Bilgic, Irem Tanriverdi, Lee Smith

Abstract read
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Article in Aging clinical and experimental research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
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1 · What the graph read from it

What it found

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2 · The registry

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3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

7 authors.

Abdulkadir KarismazDepartment of Hematology, University of Health Sciences, Istanbul Training and Research Hospital, İstanbul, Turkey.
Pinar SoysalDepartment of Geriatric Medicine, Faculty of Medicine, Bezmialem Vakif University, Istanbul, Turkey.
Rafet ErenDepartment of Hematology, Faculty of Medicine, Biruni University, Biruni University Hospital, Istanbul, Turkey.
Istemi SerinDepartment of Hematology, University of Health Sciences, Istanbul Basaksehir Cam and Sakura City Hospital, Istanbul, Turkey.
Irem BilgicDepartment of Geriatric Medicine, Faculty of Medicine, Bezmialem Vakif University, Istanbul, Turkey.
Irem TanriverdiDepartment of Geriatric Medicine, Faculty of Medicine, Bezmialem Vakif University, Istanbul, Turkey.
Lee SmithCentre for Health Performance and Wellbeing, Anglia Ruskin University, Cambridge, UK. lee.smith@aru.ac.uk.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimThis research sought to investigate the possible connection between anemia and various parameters of comprehensive geriatric assessment in elderly individuals diagnosed with Dementia with Lewy Bodies (DLB). To our knowledge, this investigation represents the first attempt to examine how anemia impacts patients suffering from DLB.

methodsThis cross-sectional study encompassed 147 DLB patients from a single geriatric outpatient clinic. The study defined anemia as hemoglobin levels under 12 g/dL for women and 13 g/dL for men. Patients' demographic information, coexisting medical conditions, and results from comprehensive geriatric evaluations were also recorded.

resultsParticipants in the study had an average age of 85.4 ± 7.1 years. Anemia was present in 46.9% of the patients. Significant disparities were noted between individuals with and without anemia regarding the occurrence of congestive heart failure (CHF), polypharmacy, geriatric depression, and insomnia (all p < 0.05). After controlling for age, gender, and CHF in the multivariate analysis, the association between anemia and both the quantity of medications used [OR: 1.15 (95% CI:1.01-1,31)] and Geriatric Depression Scale-15 scores [OR: 0.88, 95% CI: 0.78-0.98] remained statistically significant (p < 0.05) when comparing anemic patients to non-anemic individuals.

conclusionIn the present study almost one in two older patients with DLB were anemic. Anemia is associated with presence of CHF, higher number of drugs and depressive mood in DLB. It is recommended that healthcare providers should recognize the importance of anemia and its associated effects when treating older adults with DLB. This approach may lead to more effective management and treatment of this complex condition.

Indexed as

AnemiaLewy Body DiseaseAgedAged, 80 and overCross-Sectional StudiesDepressionFemaleGeriatric AssessmentHeart FailureHemoglobinsHumansMalePolypharmacyHemoglobinsAnemiaDementia with lewy bodiesGeriatric depressionPolypharmacy

Identifiers

PMID39964627
PMCPMC11835966

What Socratic holds

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.