Evidence map›Paper›PMID 39965074›Full record

ArticleAmerican journal of respiratory and critical care medicine2025

Prenatal VEGF Nanodelivery Reverses Congenital Diaphragmatic Hernia-associated Pulmonary Abnormalities.

Stavros P Loukogeorgakis, Federica Michielin, Noura Al-Juffali, Julio Jimenez, Soichi Shibuya, Jessica Allen-Hyttinen, Mary Patrice Eastwood, Ahmed S N Alhendi, Joseph Davidson, Eleonora Naldi and 22 more

Abstract read
In one paragraph

Article in American journal of respiratory and critical care medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Review
  2. VEGF-based Therapy for Congenital Diaphragmatic Hernia: A Breakthrough or a Hidden Risk?American journal of respiratory and critical care medicine · 2025
    Article
  3. Article
  4. Review
  5. Article
  6. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

32 authors.

Stavros P LoukogeorgakisStem Cells and Regenerative Medicine.ORCID 0000-0002-2960-5252
Federica MichielinStem Cells and Regenerative Medicine.ORCID 0000-0003-2065-6851
Noura Al-JuffaliUCL Respiratory, Division of Medicine, and.
Julio JimenezDepartment of Development and Regeneration, Woman and Child, Group Biomedical Sciences, and.
Soichi ShibuyaStem Cells and Regenerative Medicine.
Jessica Allen-HyttinenUCL Respiratory, Division of Medicine, and.
Mary Patrice EastwoodDepartment of Development and Regeneration, Woman and Child, Group Biomedical Sciences, and.
Ahmed S N AlhendiUCL Respiratory, Division of Medicine, and.
Joseph DavidsonStem Cells and Regenerative Medicine.
Eleonora NaldiStem Cells and Regenerative Medicine.
Panagiotis MaghsoudlouStem Cells and Regenerative Medicine.
Alfonso TedeschiStem Cells and Regenerative Medicine.
Sahira KhalafStem Cells and Regenerative Medicine.
Manuela PlatéUCL Respiratory, Division of Medicine, and.
Camila FachinCenter for Fetal Research, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania.
Andre Dos Santos DiasCenter for Fetal Research, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania.
Nikhil SindhwaniDepartment of Development and Regeneration, Woman and Child, Group Biomedical Sciences, and.
Dominic ScaglioniStem Cells and Regenerative Medicine.
Theodoros XenakisGenetics and Genomic Medicine, and.
Neil SebirePopulation, Policy and Practice, Great Ormond Street Institute of Child Health.
Monica GiomoDepartment of Industrial Engineering, University of Padova, Padova, Italy.
Simon EatonStem Cells and Regenerative Medicine.
Jaan ToelenDepartment of Development and Regeneration, Woman and Child, Group Biomedical Sciences, and.
Camilla LuniDepartment of Civil, Chemical, Environmental and Materials Engineering, University of Bologna, Bologna, Italy.
Piero PavanDepartment of Industrial Engineering, University of Padova, Padova, Italy.
Peter CarmelietLaboratory of Angiogenesis and Vascular Metabolism, Department of Oncology, KU Leuven, Leuven, Belgium.
Francesca RussoDepartment of Development and Regeneration, Woman and Child, Group Biomedical Sciences, and.
Samuel JanesUCL Respiratory, Division of Medicine, and.
Marko Z NikolićUCL Respiratory, Division of Medicine, and.
Nicola ElvassoreStem Cells and Regenerative Medicine.
Jan DeprestResearch Department of Maternal Fetal Medicine, UCL Institute for Women's Health, University College London, London, United Kingdom.
Paolo De CoppiStem Cells and Regenerative Medicine.ORCID 0000-0002-1659-0207

Funding

Engineering and Physical Sciences Research Council NS/A000027/1Erasmus+ 2013-0040LongfondsUniversitaire Ziekenhuizen Leuven, KU Leuven C32/17/054Wellcome TrustWellcome Trust 098539/Z/12/ZWellcome Trust BREATH Consortium for Lung Regeneration
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Hernias, Diaphragmatic, CongenitalLungVascular Endothelial Growth Factor AAnimalsFemaleHumansNanoparticlesPregnancyRatsVascular Endothelial Growth Factor Aalveolar epitheliumcongenital diaphragmatic herniamechanical compressionnanoparticlesVEGF

Identifiers

PMID39965074
PMCPMC12175942

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.