Evidence map›Paper›PMID 39965085›Full record

ArticleAdvanced science (Weinheim, Baden-Wurttemberg, Germany)2025

Unlocking the Promise of Antitumor Hyperthermia-Immunotherapy with Spiky Surface Topology.

Muyue Yang, Yan Yu, Tongxin Ge, Qiuyi Zhu, Ai Zhuang, Wenxing Wang, Xianqun Fan

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Advanced science (Weinheim, Baden-Wurttemberg, Germany), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Unlocking the Promise of Antitumor Hyperthermia-Immunotherapy with Spiky Surface Topology.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025
    Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Muyue YangDepartment of Ophthalmology, Shanghai Ninth People's Hospital, Shanghai JiaoTong University School of Medicine, Shanghai, 200011, China.
Yan YuDepartment of Chemistry, State Key Laboratory of Molecular Engineering of Polymers, Laboratory of Advanced Materials, Fudan University, Shanghai, 200433, China.
Tongxin GeDepartment of Ophthalmology, Shanghai Ninth People's Hospital, Shanghai JiaoTong University School of Medicine, Shanghai, 200011, China.
Qiuyi ZhuDepartment of Ophthalmology, Shanghai Ninth People's Hospital, Shanghai JiaoTong University School of Medicine, Shanghai, 200011, China.
Ai ZhuangDepartment of Ophthalmology, Shanghai Ninth People's Hospital, Shanghai JiaoTong University School of Medicine, Shanghai, 200011, China.
Wenxing WangDepartment of Chemistry, State Key Laboratory of Molecular Engineering of Polymers, Laboratory of Advanced Materials, Fudan University, Shanghai, 200433, China.
Xianqun FanDepartment of Ophthalmology, Shanghai Ninth People's Hospital, Shanghai JiaoTong University School of Medicine, Shanghai, 200011, China.ORCID https://orcid.org/0000-0002-9394-3969

Funding

China Postdoctoral Science Foundation 2024M752046Science and Technology Commission of Shanghai 20DZ2270800Science and Technology Commission of Shanghai 23ZR1438400Science and Technology Commission of Shanghai 24ZR1405900Shanghai Eye Disease Research Center 2022ZZ01003Shanghai Jiao Tong University YG2023QNB15Shanghai Ninth People's Hospital JYJC202210,JYHJB202305
6 · The paper itself

Abstract

Uveal melanoma (UM) is the most prevalent primary intraocular malignant tumor in adults with high mortality rate. Recently, immunotherapy has shown great success in other tumors, however, its therapeutic effect in UM is unsatisfactory, possibly due to the insufficient immune cell infiltration and low immunogenicity of UM. Thus, an efficient therapeutic strategy to reverse the immunosuppressive tumor microenvironment is required. Herein, a PD-L1 modified hierarchical structure consisting of a magnetic Fe

Indexed as

Hyperthermia, InducedImmunotherapyMelanomaUveal NeoplasmsAnimalsB7-H1 AntigenCell Line, TumorHumansMiceTumor MicroenvironmentUveal MelanomaB7-H1 Antigenimmunotherapymagnetic hyperthermiaspiky particlesuveal melanoma

Identifiers

PMID39965085
PMCPMC11984835

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.