Evidence map›Paper›PMID 39966413›Full record

ArticleScientific reports2025

Impact of short wavelength light exposure on body weight, mobility, anxiety like behaviour and cytokine expression.

Heba Al-Hussaini, Mohammed Al-Onaizi, Bara S Abed, Michael B Powner, Sonia M Hasan, Glen Jeffery

Abstract read
In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Heba Al-HussainiDepartment of Anatomy, College of Medicine, Kuwait University, Kuwait City, Kuwait. Heba.alhussaini@ku.edu.kw.
Mohammed Al-OnaiziDepartment of Anatomy, College of Medicine, Kuwait University, Kuwait City, Kuwait.
Bara S AbedDepartment of Anatomy, College of Medicine, Kuwait University, Kuwait City, Kuwait.
Michael B PownerCentre for Applied Vision Research, School of Health and Medical Sciences, City St George's, University of London, London, UK.
Sonia M HasanDepartment of Physiology, College of Medicine, Kuwait University, Kuwait City, Kuwait.
Glen JefferyInstitute of Ophthalmology, University College London, London, UK.

Funding

Kuwait University Research Sector grant number MA01/22Research Core Facility Kuwait University SRUL02/13
6 · The paper itself

Abstract

Mitochondria absorb short wavelengths around 420 nm. This is associated with reduced ATP and restricted mobility. The 420-450 nm range is a significant element of LED lighting and computer monitors. Here we expose freely moving mice to 420-450 nm lighting and show rapidly weight gain within a week. This may be due to reduced mitochondrial demand for circulating carbohydrates. Both groups displayed marked shifts in serum cytokines. Open field mobility was examined. The distance travelled was similar between both experimental groups and their controls. However, both experimental groups showed avoidance of central regions consistent with anxiety-like behaviours. This was significant in the 420 nm group whose wavelength exposure is closer to peak mitochondrial absorbance. These data demonstrate the potential hazards of exposure to specific short wavelengths in the visual range now common in the built environment. Data are consistent with a wider literature on systemic problems arising from exposure to short wavelength light.

Indexed as

AnxietyBehavior, AnimalBody WeightCytokinesLightAnimalsMaleMiceMitochondriaCytokines

Identifiers

PMID39966413
PMCPMC11836126

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.