Evidence map›Paper›PMID 39967626›Full record

ArticleACS medicinal chemistry letters2025

Novel Cyclohexyl Amido Acid Antagonists of Lysophosphatidic Acid Type 1 Receptor for the Treatment of Pulmonary Fibrosis.

Marta Giuliani, Andrea Rizzi, Mafalda Pagano, Luca F Raveglia, Francesca Saccani, Maria Rosaria Di Lascia, Margherita Interlandi, Tonia Simona Nardella, Gessica Marchini, Annalisa Murgo and 12 more

Abstract read
In one paragraph

Article in ACS medicinal chemistry letters, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Discovery ofJournal of medicinal chemistry · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

22 authors.

Marta GiulianiChiesi Farmaceutici S.p.A, Centro Ricerche, Largo Belloli 11/a, 43122 Parma, Italy.ORCID https://orcid.org/0000-0002-1226-5546
Andrea RizziChiesi Farmaceutici S.p.A, Centro Ricerche, Largo Belloli 11/a, 43122 Parma, Italy.ORCID https://orcid.org/0000-0001-5491-5343
Mafalda PaganoAptuit, an Evotec Company, Via Alessandro Fleming 4, 37135 Verona, Italy.
Luca F RavegliaAptuit, an Evotec Company, Via Alessandro Fleming 4, 37135 Verona, Italy.
Francesca SaccaniChiesi Farmaceutici S.p.A, Centro Ricerche, Largo Belloli 11/a, 43122 Parma, Italy.
Maria Rosaria Di LasciaChiesi Farmaceutici S.p.A, Centro Ricerche, Largo Belloli 11/a, 43122 Parma, Italy.
Margherita InterlandiChiesi Farmaceutici S.p.A, Centro Ricerche, Largo Belloli 11/a, 43122 Parma, Italy.
Tonia Simona NardellaChiesi Farmaceutici S.p.A, Centro Ricerche, Largo Belloli 11/a, 43122 Parma, Italy.
Gessica MarchiniChiesi Farmaceutici S.p.A, Centro Ricerche, Largo Belloli 11/a, 43122 Parma, Italy.
Annalisa MurgoChiesi Farmaceutici S.p.A, Centro Ricerche, Largo Belloli 11/a, 43122 Parma, Italy.
Laura TigliChiesi Farmaceutici S.p.A, Centro Ricerche, Largo Belloli 11/a, 43122 Parma, Italy.
Alice PappaniChiesi Farmaceutici S.p.A, Centro Ricerche, Largo Belloli 11/a, 43122 Parma, Italy.
Anna Maria CapelliChiesi Farmaceutici S.p.A, Centro Ricerche, Largo Belloli 11/a, 43122 Parma, Italy.
Sergio Xanxo FernandezChiesi Farmaceutici S.p.A, Centro Ricerche, Largo Belloli 11/a, 43122 Parma, Italy.
Paola PucciniChiesi Farmaceutici S.p.A, Centro Ricerche, Largo Belloli 11/a, 43122 Parma, Italy.
Gino VillettiChiesi Farmaceutici S.p.A, Centro Ricerche, Largo Belloli 11/a, 43122 Parma, Italy.
Maurizio CivelliChiesi Farmaceutici S.p.A, Centro Ricerche, Largo Belloli 11/a, 43122 Parma, Italy.
Claudia BeatoAptuit, an Evotec Company, Via Alessandro Fleming 4, 37135 Verona, Italy.
Elisa MoroAptuit, an Evotec Company, Via Alessandro Fleming 4, 37135 Verona, Italy.
Claudia MundiAptuit, an Evotec Company, Via Alessandro Fleming 4, 37135 Verona, Italy.
Rosaria RemelliAptuit, an Evotec Company, Via Alessandro Fleming 4, 37135 Verona, Italy.
Elisabetta ArmaniChiesi Farmaceutici S.p.A, Centro Ricerche, Largo Belloli 11/a, 43122 Parma, Italy.ORCID https://orcid.org/0000-0002-2835-2652

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Lysophosphatidic acid (LPA) is a phospholipid activating different biological functions by binding to G protein-coupled receptors (LPA

Identifiers

PMID39967626
PMCPMC11831564

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.