Evidence map›Paper›PMID 39968776›Full record

ArticleJournal of the American Heart Association2025

Incremental Prognostic Value of Echocardiography Measures of Right Ventricular Systolic Function in Patients With Chronic Heart Failure.

Francesco Gentile, Michela Chianca, Lorenzo Bazan, Paolo Sciarrone, Vlad Chubuchny, Claudia Taddei, Elisa Poggianti, Claudio Passino, Michele Emdin, Alberto Giannoni

Abstract readComparative Study
In one paragraph

Article in Journal of the American Heart Association, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Utilizing bedside VExUS and the S-prime velocity for real-time assessment of venous congestion on right ventricular function in heart failure.The Egyptian heart journal : (EHJ) : official bulletin of the Egyptian Society of Cardiology · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Francesco GentileHealth Science Interdisciplinary Center Scuola Superiore Sant'Anna Pisa Italy.ORCID 0000-0001-7453-3748
Michela ChiancaHealth Science Interdisciplinary Center Scuola Superiore Sant'Anna Pisa Italy.ORCID 0000-0001-8446-8927
Lorenzo BazanHealth Science Interdisciplinary Center Scuola Superiore Sant'Anna Pisa Italy.ORCID 0009-0001-4801-9996
Paolo SciarroneHealth Science Interdisciplinary Center Scuola Superiore Sant'Anna Pisa Italy.ORCID 0000-0002-8803-4533
Vlad ChubuchnyFondazione Toscana Gabriele Monasterio Pisa Italy.ORCID 0000-0001-9204-7006
Claudia TaddeiFondazione Toscana Gabriele Monasterio Pisa Italy.
Elisa PoggiantiFondazione Toscana Gabriele Monasterio Pisa Italy.
Claudio PassinoHealth Science Interdisciplinary Center Scuola Superiore Sant'Anna Pisa Italy.ORCID 0000-0002-0723-4753
Michele EmdinHealth Science Interdisciplinary Center Scuola Superiore Sant'Anna Pisa Italy.ORCID 0000-0002-8541-1962
Alberto GiannoniHealth Science Interdisciplinary Center Scuola Superiore Sant'Anna Pisa Italy.ORCID 0000-0001-9314-2005

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTricuspid annular plane systolic excursion (TAPSE), Doppler tissue imaging-derived tricuspid lateral annular systolic wave velocity (S'), and right ventricular fractional area change (RV-FAC) are the most widely used echocardiographic measures of right ventricular systolic function. This study aimed to compare the prognostic value of TAPSE, S', and RV-FAC in a large cohort of patients with chronic heart failure.

methodsConsecutive outpatients with heart failure and left ventricular ejection fraction <50% on guideline-recommended therapies undergoing echocardiography were followed up for the end point of cardiac and all-cause death.

resultsAmong 1590 patients (71±12 years, 77% men, left ventricular ejection fraction 34%±9%), 202 (13%) died from cardiac causes during a median follow-up of 28 (interquartile range, 14-40) months. According to the recommended cut points for TAPSE (<17 mm), S' (<9.5 cm/s), or RV-FAC (<35%), right ventricular systolic dysfunction was found in 37%, 40%, and 35% of patients, respectively, with 21%, 31%, and 33% of discordant cases comparing TAPSE versus S', TAPSE versus RV-FAC, and S' versus RV-FAC. Both TAPSE <17 mm and RV-FAC <35% were more accurate than S' <9.5 cm/s in predicting the risk of cardiac death (

conclusionsIn patients with chronic heart failure and left ventricular ejection fraction <50%, TAPSE, and RV-FAC are more accurate than S' in predicting the risk of cardiac and all-cause death. Considering both RV-FAC and TAPSE provides incremental prognostic value.

Indexed as

EchocardiographyHeart FailureTricuspid ValveVentricular Function, RightAgedAged, 80 and overChronic DiseaseFemaleHumansMaleMiddle AgedPrognosisStroke Volumeechocardiographyheart failureoutcomeright ventricleRV‐FACS′TAPSE

Identifiers

PMID39968776
PMCPMC12132635

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.