Evidence map›Paper›PMID 39968950›Full record

ArticleDatabase : the journal of biological databases and curation2025

TumorAgDB1.0: tumor neoantigen database platform.

Yan Shao, Yang Gao, Ling-Yu Wu, Shu-Guang Ge, Peng-Bo Wen

Abstract read
In one paragraph

Article in Database : the journal of biological databases and curation, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Yan ShaoSchool of Medical Infand Engineering, Xuzhou Medical University, No. 209, Tongshan Road, Yunlong District, Xuzhou, Jiangsu 221004, China.
Yang GaoDepartment of Histology and Embryology, Shantou University Medical College, No. 243, Daxue Road, Shantou, Guangdong 515063, China.
Ling-Yu WuSchool of Medical Infand Engineering, Xuzhou Medical University, No. 209, Tongshan Road, Yunlong District, Xuzhou, Jiangsu 221004, China.
Shu-Guang GeSchool of Medical Infand Engineering, Xuzhou Medical University, No. 209, Tongshan Road, Yunlong District, Xuzhou, Jiangsu 221004, China.
Peng-Bo WenSchool of Medical Infand Engineering, Xuzhou Medical University, No. 209, Tongshan Road, Yunlong District, Xuzhou, Jiangsu 221004, China.ORCID 0000-0002-3017-0137

Funding

Initializing Fund of Xuzhou Medical University D2020040National Natural Science Foundation of China 32100998 32201016 JSSCBS20211265
6 · The paper itself

Abstract

With the continuous advancements in cancer immunotherapy, neoantigen-based therapies have demonstrated remarkable clinical efficacy. However, accurately predicting the immunogenicity of neoantigens remains a significant challenge. This is mainly due to two core factors: the scarcity of high-quality neoantigen datasets and the limited prediction accuracy of existing immunogenicity prediction tools. This study addressed these issues through several key steps. First, it collected and organized immunogenic neoantigen peptide data from publicly available literature and neoantigen databases. Second, it analyzed the data to identify key features influencing neoantigen immunogenicity prediction. Finally, it integrated existing prediction tools to create TumorAgDB1.0, a comprehensive tumor neoantigen database. TumorAgDB1.0 offers a user-friendly platform. Users can efficiently search for neoantigen data using parameters like amino acid sequence and peptide length. The platform also offers detailed information on the characteristics of neoantigens and tools for predicting tumor neoantigen immunogenicity. Additionally, the database includes a data download function, allowing researchers to easily access high-quality data to support the development and improvement of neoantigen immunogenicity prediction tools. In summary, TumorAgDB1.0 is a powerful tool for neoantigen screening and validation in tumor immunotherapy. It offers strong support to researchers. Database URL: https://tumoragdb.com.cn.

Indexed as

Antigens, NeoplasmDatabases, ProteinNeoplasmsHumansImmunotherapyAntigens, Neoplasm

Identifiers

PMID39968950
PMCPMC11836679

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.