Evidence map›Paper›PMID 39969973›Full record

ArticleMolecular biology of the cell2025

Phyloproteomics reveals conserved patterns of axonemal dynein methylation across the motile ciliated eukaryotes.

Miho Sakato-Antoku, Nikisha Patel, Mayu Inaba, Qinhui Rao, Jun Yang, Ramila S Patel-King, Kazuo Inaba, Jeremy L Balsbaugh, Stephen M King

Abstract read
In one paragraph

Article in Molecular biology of the cell, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Miho Sakato-AntokuDepartment of Molecular Biology and Biophysics, University of Connecticut Health Center, Farmington, CT 06030-3305.
Nikisha PatelDepartment of Biology, Trinity College, Hartford, CT 06106.
Mayu InabaDepartment of Cell Biology, University of Connecticut Health Center, Farmington, CT 06030.
Qinhui RaoDepartment of Molecular Biophysics and Biochemistry, Yale University, New Haven, CT 06511.
Jun YangDepartment of Molecular Biophysics and Biochemistry, Yale University, New Haven, CT 06511.
Ramila S Patel-KingDepartment of Molecular Biology and Biophysics, University of Connecticut Health Center, Farmington, CT 06030-3305.
Kazuo InabaShimoda Marine Research Center, University of Tsukuba, Shizuoka 415-0025, Japan.
Jeremy L BalsbaughProteomics and Metabolomics Facility, Center for Open Research Resources and Equipment, University of Connecticut, Storrs, CT 06269.
Stephen M KingDepartment of Molecular Biology and Biophysics, University of Connecticut Health Center, Farmington, CT 06030-3305.ORCID 0000-0002-5484-5530

Funding

The Biology of Motile CiliaR35GM140631 · NIGMS · UNIVERSITY OF CONNECTICUT SCH OF MED/DNT · PI Stephen M King · 2021 to 2026
$4.2M
Thermo Scientific Orbitrap Eclipse Tribrid ETD Mass Spectrometer for UConn ProteomicsS10OD028445 · OD · UNIVERSITY OF CONNECTICUT STORRS · PI BALSBAUGH, JEREMY · 2021 to 2021
$994k
NIGMS NIH HHS R35 GM140631NIH HHS S10 OD028445
6 · The paper itself

Abstract

Axonemal dynein assembly occurs in the cytoplasm and numerous cytosolic factors are specifically required for this process. Recently, one factor (DNAAF3/PF22) was identified as a methyltransferase. Examination of

Indexed as

Axonemal DyneinsEukaryotaAnimalsAxonemeChlamydomonasCiliaDrosophila melanogasterMaleMethylationPhylogenyProteomicsAxonemal Dyneins

Identifiers

PMID39969973
PMCPMC12005109

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.