Evidence map›Paper›PMID 39970248›Full record

ArticleHypertension (Dallas, Tex. : 1979)2025

Mediation of Social Determinants and Hypertension by Epigenetic Age in CARDIA.

Mindy D Szeto, Hongyan Ning, Havisha Pedamallu, Yinan Zheng, Lisa Schneper, Brian Joyce, Kyeezu Kim, Kiarri N Kershaw, Orna Reges, Lifang Hou and 3 more

Abstract readLetter
In one paragraph

Article in Hypertension (Dallas, Tex. : 1979), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Mindy D SzetoDepartment of Preventive Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL (M.D.S., H.N., H.P., Y.Z., B.J., K.K., K.N.K., L.H., N.B.A., D.M.L.-J.).ORCID 0000-0003-3642-3753
Hongyan NingDepartment of Preventive Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL (M.D.S., H.N., H.P., Y.Z., B.J., K.K., K.N.K., L.H., N.B.A., D.M.L.-J.).ORCID 0000-0003-1157-6614
Havisha PedamalluDepartment of Preventive Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL (M.D.S., H.N., H.P., Y.Z., B.J., K.K., K.N.K., L.H., N.B.A., D.M.L.-J.).ORCID 0000-0002-1753-1153
Yinan ZhengDepartment of Preventive Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL (M.D.S., H.N., H.P., Y.Z., B.J., K.K., K.N.K., L.H., N.B.A., D.M.L.-J.).ORCID 0000-0002-2006-7320
Lisa SchneperDepartment of Molecular Biology, Princeton University, NJ (L.S., D.A.N.).
Brian JoyceDepartment of Preventive Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL (M.D.S., H.N., H.P., Y.Z., B.J., K.K., K.N.K., L.H., N.B.A., D.M.L.-J.).ORCID 0000-0002-5271-6161
Kyeezu KimDepartment of Preventive Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL (M.D.S., H.N., H.P., Y.Z., B.J., K.K., K.N.K., L.H., N.B.A., D.M.L.-J.).ORCID 0000-0002-9094-9011
Kiarri N KershawDepartment of Preventive Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL (M.D.S., H.N., H.P., Y.Z., B.J., K.K., K.N.K., L.H., N.B.A., D.M.L.-J.).ORCID 0000-0002-0063-6397
Orna RegesDepartment of Health Systems Management, Ariel University, Ariel, Israel (O.R.).ORCID 0000-0002-5384-005X
Lifang HouDepartment of Preventive Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL (M.D.S., H.N., H.P., Y.Z., B.J., K.K., K.N.K., L.H., N.B.A., D.M.L.-J.).ORCID 0000-0003-4877-0031
Norrina B AllenDepartment of Preventive Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL (M.D.S., H.N., H.P., Y.Z., B.J., K.K., K.N.K., L.H., N.B.A., D.M.L.-J.).ORCID 0000-0002-6993-4384
Daniel A NottermanDepartment of Molecular Biology, Princeton University, NJ (L.S., D.A.N.).ORCID 0000-0002-8809-8297
Donald M Lloyd-JonesDepartment of Preventive Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL (M.D.S., H.N., H.P., Y.Z., B.J., K.K., K.N.K., L.H., N.B.A., D.M.L.-J.).ORCID 0000-0003-0847-6110

Funding

CORONARY ARTERY RISK DEVELOPMENT IN YOUNG ADULTS (CARDIA) STUDY - COORDINATING CENTER (CC)75N92023D00002 · NHLBI · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI LI, JING · 2023 to 2025
$6.8M
Reciprocal Genetic-Environmental Interactions During Childhood and AdolescenceR01HD076592 · NICHD · PRINCETON UNIVERSITY · PI NOTTERMAN, DANIEL A. · 2013 to 2023
$6.8M
CORONARY ARTERY RISK DEVELOPMENT IN YOUNG ADULTS (CARDIA) STUDY - OAKLAND FIELD CENTER75N92023D00003 · NHLBI · KAISER FOUNDATION RESEARCH INSTITUTE · PI BHATT, ANKEET S. · 2023 to 2025
$2.2M
CORONARY ARTERY RISK DEVELOPMENT IN YOUNG ADULTS (CARDIA) STUDY - BIRMINGHAM FIELD CENTER75N92023D00005 · NHLBI · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI LEWIS, CORA · 2023 to 2025
$2.2M
CORONARY ARTERY RISK DEVELOPMENT IN YOUNG ADULTS (CARDIA) STUDY - CHICAGO FIELD CENTERDIVERSITY SUPPLEMENT FOR MORGANN WEST75N92023D00004 · NHLBI · NORTHWESTERN UNIVERSITY · PI CARNETHON, MERCEDES · 2023 to 2025
$2.1M
CORONARY ARTERY RISK DEVELOPMENT IN YOUNG ADULTS (CARDIA) STUDY - UNIVERSITY OF MINNESOTA FIELD CENTER.75N92023D00006 · NHLBI · UNIVERSITY OF MINNESOTA · PI SCHREINER, PAMELA J · 2023 to 2025
$1.7M
Social Determinants and Epigenetic Mediators of Hypertension in the Future of Families and Child Wellbeing StudyF31HL173991 · NHLBI · NORTHWESTERN UNIVERSITY AT CHICAGO · PI Mindy Szeto · 2024 to 2026
$134k
NHLBI NIH HHS 75N92023D00002NHLBI NIH HHS 75N92023D00003NHLBI NIH HHS 75N92023D00004NHLBI NIH HHS 75N92023D00005NHLBI NIH HHS 75N92023D00006NHLBI NIH HHS F31 HL173991NICHD NIH HHS R01 HD076592
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

biomarkersDNA methylationepigenomicshypertensionmediation analysissocial determinants of healthsocioeconomic disparities in health

Identifiers

PMID39970248
PMCPMC11841923

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.