Evidence map›Paper›PMID 39971373›Full record

ReviewZhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery2025

[Application and progress of intelligent responsive hydrogels in articular cartilage injury repair].

Qingyu Xu, Baojian Zhang, Hongri Li, Chengri Liu, Shuhao Bi, Zhixiang Yang, Yanqun Liu

Abstract readReviewEnglish Abstract
In one paragraph

Review in Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Qingyu XuOrthopedic Diagnosis and Treatment Center, Yanbian University Hospital (Yanbian Hospital), Yanji Jilin, 133000, P. R. China.
Baojian ZhangOrthopedic Diagnosis and Treatment Center, Yanbian University Hospital (Yanbian Hospital), Yanji Jilin, 133000, P. R. China.
Hongri LiOrthopedic Diagnosis and Treatment Center, Yanbian University Hospital (Yanbian Hospital), Yanji Jilin, 133000, P. R. China.
Chengri LiuOrthopedic Diagnosis and Treatment Center, Yanbian University Hospital (Yanbian Hospital), Yanji Jilin, 133000, P. R. China.
Shuhao BiOrthopedic Diagnosis and Treatment Center, Yanbian University Hospital (Yanbian Hospital), Yanji Jilin, 133000, P. R. China.
Zhixiang YangOrthopedic Diagnosis and Treatment Center, Yanbian University Hospital (Yanbian Hospital), Yanji Jilin, 133000, P. R. China.
Yanqun LiuOrthopedic Diagnosis and Treatment Center, Yanbian University Hospital (Yanbian Hospital), Yanji Jilin, 133000, P. R. China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: To review clinical application and research progress of different types of intelligent responsive hydrogels in repairing articular cartilage injury. Methods: The animal experiments and clinical studies of different types of intelligent responsive hydrogels for repairing articular cartilage injury were summarized by reviewing relevant literature at home and abroad. Results: The intrinsic regenerative capacity of articular cartilage following injury is limited. Intelligent responsive hydrogels, including those that are temperature-sensitive, light-sensitive, enzyme-responsive, pH-sensitive, and other stimuli-responsive hydrogels, can undergo phase transitions in response to specific stimuli, thereby achieving optimal functionality. These hydrogels can fill the injured cartilage area, promote the proliferation and differentiation of chondrocytes, and expedite the repair of the damaged site. With advancements in cartilage tissue engineering materials research, intelligent responsive hydrogels offer a novel approach and promising potential for the treatment of cartilage injuries. Conclusion: Intelligent responsive hydrogel is a kind of flexible, controllable, efficient, and stable polymer, which has similar structure and functional properties to articular cartilage, and has become one of the important biomaterials for cartilage repair. However, there is still a lack of unified treatment standards and simple and efficient preparation technology.

Indexed as

Biocompatible MaterialsCartilage, ArticularHydrogelsTissue EngineeringAnimalsChondrocytesHumansTissue ScaffoldsBiocompatible MaterialsHydrogelscartilage injuryIntelligent responsive hydrogelrepairresponse principle

Identifiers

PMID39971373
PMCPMC11839296

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.