Trial reportJournal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing2025
Insights from optimal high-power ablation settings for anterior pulmonary vein wall isolation-A-Q-RATE POWER Trial.
Trial report in Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
3 citing papers in PubMed.
- Ablation lesion patterns in atrial fibrillation: A cardiac MRI comparison of different ablation strategies.Heart rhythm O2 · 2026Article
- Efficacy and Safety of Catheter Ablation for Atrial Arrhythmias in Solid Organ Transplant Recipients: A Single-Center Experience.Clinical cardiology · 2026Article
- Very high power short duration as re-ablation strategy for recurrent atrial fibrillation.BMC cardiovascular disorders · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe radiofrequency (RF) lesions obtained using very high-power short-duration (vHPSD) are shallower compared to high-power sort-duration (HPSD) or conventional ablation settings. Thus, there is a possibility that vHPSD RF applications may not achieve transmurality at thick parts of the anterior aspects of the pulmonary vein (PV)-left atrial (LA) wall junction. The aim of the study was to compare acute efficacy of pulmonary vein isolation (PVI) using vHPSD versus HPSD guided by AI ablation at the anterior aspects of PV in patients undergoing atrial fibrillation (AF) ablation.
methodsThe A-Q-RATE POWER Trial was a prospective, dual-center, randomized study. Patients were assigned to receive vHPSD versus HPSD ablation delivered at the anterior aspects of PV. In both arms, the posterior parts of PV were ablated with vHPSD. The primary outcome was the need for additional RF applications at the anterior aspect of PVs to achieve complete PVI.
resultsSeventy patients were randomly assigned to vHPSD (n = 35) or HPSD (n = 35). The vHPSD group required more touch-up RF applications at the anterior aspects of PV than the HPSD group (46% vs 19%, p < 0.001), especially at the right PVs (57% vs 20%, p = 0.001) compared to the left PVs (34% vs 17%, p = 0.1). The median duration of the procedure, LA dwell time, and fluoroscopy time were similar in both groups (112 [IQR 90-130] min vs 107 [90-125] min, p = 0.58; 95 [70-106] min vs 90 [71-100] min, p = 0.55; and 28 [IQR 14-69] s vs 46 [IQR 0-89] s, p = 0.97,respectively).
conclusionThe proposed hybrid strategy is associated with a significantly lower need for additional touch-up RF applications than vHPSD only, without extending procedural and fluoroscopy duration.
Indexed as
Identifiers
39971843What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.