Evidence map›Paper›PMID 39973441›Full record

ArticleClinical hemorheology and microcirculation2025

Hypoxic human adipose mesenchymal stem cells-derived extracellular vesicles induce P311 expression and inhibit activation and injury of human brain microvascular endothelial cells.

Yun Zhang, Hanghang Zhao, Yu Su, Shudong Yang, Tao Kang, Li Li

RetractedAbstract readRetracted Publication
PubMed Publisher
In one paragraph

Article in Clinical hemorheology and microcirculation, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It has been retracted, and should not be counted. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

  • Retraction · 2025-11-23Compromised Peer Review · Concerns/Issues about Referencing/Attributions · Concerns/Issues about Third Party Involvement · Investigation by Journal/Publisher ·
  • Retracted
5 · Who and what money

Authors and funding

6 authors.

Yun ZhangHospital for Chronic Neurological diseases, Xi'an International Medical Center Hospital Affiliated to Northwest University, Xi'an, China.
Hanghang ZhaoHospital for Chronic Neurological diseases, Xi'an International Medical Center Hospital Affiliated to Northwest University, Xi'an, China.
Yu SuHospital for Chronic Neurological diseases, Xi'an International Medical Center Hospital Affiliated to Northwest University, Xi'an, China.
Shudong YangHospital for Chronic Neurological diseases, Xi'an International Medical Center Hospital Affiliated to Northwest University, Xi'an, China.
Tao KangHospital for Chronic Neurological diseases, Xi'an International Medical Center Hospital Affiliated to Northwest University, Xi'an, China.
Li LiHospital for Chronic Neurological diseases, Xi'an International Medical Center Hospital Affiliated to Northwest University, Xi'an, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

ObjectiveStem cell therapy can modify angiogenic pathways. Neural protein 3.1 (P311) possesses the pro-angiogenic property. This study strived to explore the action and mechanism of human adipose mesenchymal stem cells (hADSCs) in human brain microvascular endothelial cell (hBMEC) injury by regulating P311.MethodsThe hADSCs of the 3

Indexed as

Adipose TissueBrainEndothelial CellsExtracellular VesiclesMesenchymal Stem CellsCell DifferentiationCell HypoxiaCells, CulturedHumansangiogenesisextracellular vesicleshuman adipose mesenchymal stem cellshuman brain microvascular endothelial cellshypoxic microenvironmentlipopolysaccharidemigrationproliferation

Identifiers

PMID39973441

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.