Evidence mapPaperPMID 39974643Full record

ArticleACS pharmacology & translational science2025

Identification of a Cannabinoid Receptor 2 Allosteric Site Using Computational Modeling and Pharmacological Analysis.

Zara Farooq, Pietro Delre, Stylianos Iliadis, Giuseppe Felice Mangiatordi, Marialessandra Contino, Lesley A Howell, Peter J McCormick

Abstract read
In one paragraph

Article in ACS pharmacology & translational science, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Zara FarooqCentre for Endocrinology, William Harvey Research Institute, Bart's and The London School of Medicine and Dentistry, Queen Mary University of London, Charterhouse Square, London EC1M 6BQ, U.K.ORCID https://orcid.org/0000-0002-9925-9797
Pietro DelreCNR-Institute of Crystallography, Via Amendola 122/o, Bari 70126, Italy.
Stylianos IliadisSchool of Physical and Chemical Sciences, Queen Mary University of London, Mile End Road, London E1 4NS, U.K.
Giuseppe Felice MangiatordiCNR-Institute of Crystallography, Via Amendola 122/o, Bari 70126, Italy.ORCID https://orcid.org/0000-0003-4042-2841
Marialessandra ContinoDepartment of Pharmacy-Drug Sciences, University of Bari Aldo Moro, Via Orabona 4, Bari 70125, Italy.ORCID https://orcid.org/0000-0002-0713-3151
Lesley A HowellSchool of Physical and Chemical Sciences, Queen Mary University of London, Mile End Road, London E1 4NS, U.K.
Peter J McCormickCentre for Endocrinology, William Harvey Research Institute, Bart's and The London School of Medicine and Dentistry, Queen Mary University of London, Charterhouse Square, London EC1M 6BQ, U.K.ORCID https://orcid.org/0000-0002-2225-5181

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Emerging evidence has demonstrated that cannabinoid receptor 2 (CB

Identifiers

PMID39974643
PMCPMC11833715

What Socratic holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.