Evidence map›Paper›PMID 39974657›Full record

ArticleJournal of tissue engineering

Transplantation of engineered endothelial progenitor cells with H19 overexpression promotes arterial reendothelialization and inhibits neointimal hyperplasia.

Yanchen Ye, Lin Huang, Kangjie Wang, Yunhao Sun, Zhihao Zhou, Tang Deng, Yunyan Liu, Rui Wang, Ridong Wu, Chen Yao

Abstract read
In one paragraph

Article in Journal of tissue engineering. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Yanchen YeDivision of Vascular Surgery, the First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China.
Lin HuangDivision of Vascular Surgery, the First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China.
Kangjie WangDivision of Vascular Surgery, the First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China.
Yunhao SunDivision of Vascular Surgery, the First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China.
Zhihao ZhouDivision of Vascular Surgery, the First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China.
Tang DengDivision of Vascular Surgery, the First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China.
Yunyan LiuDivision of Vascular Surgery, the First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China.
Rui WangDivision of Vascular Surgery, the First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China.
Ridong WuDivision of Vascular Surgery, the First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China.
Chen YaoDivision of Vascular Surgery, the First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China.ORCID https://orcid.org/0000-0003-0327-9599

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Endothelial injury is a key factor initiating in-stent restenosis (ISR) following peripheral artery stent implantation. Genetically modified endothelial progenitor cells (EPCs) can promote reendothelialization of injured arteries and inhibit neointimal hyperplasia. However, the role of engineered EPCs overexpressing lncRNA H19 in these processes remains unclear. We constructed EPCs overexpressing lncRNA H19 and investigated their effects and mechanisms in promoting reendothelialization and inhibiting neointimal hyperplasia both

Indexed as

endothelial progenitor cellsLncRNA H19neointimal hyperplasiareendothelialization

Identifiers

PMID39974657
PMCPMC11837068

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.