ArticleAlzheimer's & dementia (New York, N. Y.)
Sick sinus syndrome and high-degree atrioventricular block in dementia with Lewy bodies and other dementia subtypes: A study of ≈ 73,000 patients with dementia.
Article in Alzheimer's & dementia (New York, N. Y.). The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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Who cites it
5 citing papers in PubMed.
- Association of Atrial Electrophysiological Abnormalities With Cognitive Decline and Cerebrovascular Disease.Journal of the American Heart Association · 2026Article
- Comorbid Pathologies and Their Impact on Dementia with Lewy Bodies-Current View.International journal of molecular sciences · 2025Review
- Myocardial sympathetic distal axon loss in subjects with Lewy pathology in three autopsy cohorts.Acta neuropathologica · 2025Article
- U-shaped association of resting heart rate with cognitive decline.Brain communications · 2025Article
- Sick sinus syndrome and high-degree atrioventricular block in dementia with Lewy bodies and other dementia subtypes: A study of ≈ 73,000 patients with dementia.Alzheimer's & dementia (New York, N. Y.)Article
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionLewy body pathology is commonly found in cardiac nervous tissue, including the cardiac conduction system. This study aimed to investigate the occurrence of sick sinus syndrome (SSS) and high-degree atrioventricular block in dementia with Lewy bodies (DLB) compared to Alzheimer's disease (AD) and other dementia subtypes.
methodsWe included 73,619 individuals diagnosed with dementia from the Swedish Dementia Registry. Data pertaining to incident pacemaker implantation was obtained from the Swedish Pacemaker Registry.
resultsSSS was more common in the DLB compared to the AD cohort (2.2% vs. 1.5%, DISCUSSION: We showed that incident pacemaker implantation secondary to SSS was more common in patients with DLB compared to those with AD. HIGHLIGHTS: Incident pacemaker implantation secondary to sick sinus syndrome (SSS; but not high-degree atrioventricular block [HAVB]) was more common in dementia with Lewy bodies (DLB) versus Alzheimer's disease (AD).In adjusted models, SSS (but not HAVB) was positively associated with DLB compared to AD.Pacemaker data of various dementia disorders are presented.
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