Evidence map›Paper›PMID 39975588›Full record

ArticleInfection and drug resistance2025

Point Prevalence Survey of Antibiotic Use in Level 1 hospitals in Zambia: Future Prospects for Antimicrobial Stewardship Programs.

Steward Mudenda, Adriano Focus Lubanga, Shazia Jamshed, Bibian Biemba, Racheal Sakala, Mervis Chiyabi, Lorraine Kavubya, Linda Twaambo Milambo, Flavien Nsoni Bumbangi, Joseph Yamweka Chizimu and 15 more

Abstract read
In one paragraph

Article in Infection and drug resistance, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

25 authors.

Steward MudendaDepartment of Pharmacy, School of Health Sciences, University of Zambia, Lusaka, Zambia.ORCID 0000-0003-1692-8981
Adriano Focus LubangaEducation and Research, Clinical Research Education and Management Services (CREAMS), Lilongwe, Malawi.ORCID 0000-0002-5491-5412
Shazia JamshedDepartment of Pharmacy Practice, School of Pharmacy, International Medical University, Kuala Lumpur, Malaysia.
Bibian BiembaDepartment of Pharmacy, School of Health Sciences, University of Zambia, Lusaka, Zambia.
Racheal SakalaDepartment of Pharmacy, School of Health Sciences, University of Zambia, Lusaka, Zambia.
Mervis ChiyabiDepartment of Pharmacy, School of Health Sciences, University of Zambia, Lusaka, Zambia.
Lorraine KavubyaDepartment of Pharmacy, School of Health Sciences, University of Zambia, Lusaka, Zambia.
Linda Twaambo MilamboDepartment of Pharmacy, School of Health Sciences, University of Zambia, Lusaka, Zambia.
Flavien Nsoni BumbangiDepartment of Medicine and Clinical Sciences, School of Medicine, Eden University, Lusaka, Zambia.ORCID 0000-0002-0731-3558
Joseph Yamweka ChizimuAntimicrobial Resistance Coordinating Committee, Zambia National Public Health Institute, Lusaka, Zambia.
Kaunda YambaAction on Antibiotic Resistance (React) Africa, Lusaka, Zambia.
Evelyn WesangulaStrengthening Pandemic Preparedness, Eastern, Central, and Southern Africa Health Community, Arusha, Tanzania.
Audrey ChigomeDepartment of Public Health Pharmacy and Management, School of Pharmacy, Sefako Makgatho Health Sciences University, Garankuwa, Pretoria, South Africa.
Aubrey Chichonyi KalungiaDepartment of Pharmacy, School of Health Sciences, University of Zambia, Lusaka, Zambia.ORCID 0000-0003-2554-1236
Israel Abebrese SefahPharmacy Practice Department, School of Pharmacy, University of Health and Allied Sciences, Volta Region, Ghana.
Zia U I MustafaDiscipline of Clinical Pharmacy, School of Pharmaceutical Sciences, Universiti Sains Malaysia, Gelugor, Penang, Malaysia.ORCID 0000-0002-8109-4859
Amos Yared MasseleDepartment of Clinical Pharmacology and Therapeutics, Kairuki University, Dar Es Salaam, Tanzania.
Zikria SaleemDepartment of Pharmacy Practice, Faculty of Pharmacy, Bahauddin Zakariya University, Multan, Pakistan.ORCID 0000-0003-3202-6347
Richard MutemwaDepartment of Public Health, School of Medicine and Health Sciences, University of Lusaka, Lusaka, Zambia.ORCID 0000-0002-3658-0233
Eustarckio KazongaDepartment of Public Health, School of Medicine and Health Sciences, University of Lusaka, Lusaka, Zambia.
Massimo SartelliDepartment of Surgery, Macerata Hospital, Macerata, Italy.
Johanna Catharina MeyerDepartment of Public Health Pharmacy and Management, School of Pharmacy, Sefako Makgatho Health Sciences University, Garankuwa, Pretoria, South Africa.
John Bwalya MumaDepartment of Disease Control, School of Veterinary Medicine, University of Zambia, Lusaka, Zambia.
Roma ChilengiAntimicrobial Resistance Coordinating Committee, Zambia National Public Health Institute, Lusaka, Zambia.
Brian GodmanDepartment of Public Health Pharmacy and Management, School of Pharmacy, Sefako Makgatho Health Sciences University, Garankuwa, Pretoria, South Africa.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: The inappropriate prescribing and use of antibiotics have contributed to the emergence and spread of antimicrobial resistance (AMR). In Zambia, there is a paucity of information on the prescribing patterns and use of antibiotics among hospitalized patients in level 1 hospitals. This study investigated antibiotic use in five level 1 hospitals in Lusaka, Zambia. Methods: This cross-sectional study utilized the World Health Organization (WHO) Point Prevalence Survey (PPS) methodology among in-patients admitted in level 1 hospitals before 08:00 a.m. on the survey day in August 2024. Data were analysed using IBM SPSS version 23.0. Results: The prevalence of antibiotic use among inpatients was 59.0%, with ceftriaxone being the most prescribed. Antibiotics were prescribed mainly for paediatrics and male inpatients. This study found that 53.0% of prescribed antibiotics were from the Access group while 38.2% were from the Watch group of the World Health Organization Access, Watch, and Reserve (AWaRe) classification. Adherence to national treatment guidelines was 36.0%, with most antibiotics prescribed empirically without evidence of culture and sensitivity tests. Conclusion: This study found a high use of antibiotics and low adherence to treatment guidelines in level 1 hospitals in Lusaka, Zambia. The findings of this study demonstrate the need to establish and strengthen antimicrobial stewardship programs and strengthen laboratory capacity to aid clinicians in diagnosing, treating, and managing patients across level 1 hospitals in Zambia.

Indexed as

antibiotic useantimicrobial resistanceantimicrobial stewardshipPoint Prevalence SurveyZambia

Identifiers

PMID39975588
PMCPMC11837744

What Socratic holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.