Evidence map›Paper›PMID 39979492›Full record

ArticlePlanta2025

Integrative analysis of the ABC gene family in sorghum revealed SbABCB11 participating in translocation of cadmium from roots to shoots.

Bo Zhang, Weitao Jia, Kangqi Lin, Sulian Lv, Zijing Guo, Wenzhu Xie, Yingjiao He, Yinxin Li

Abstract read
PubMed Publisher
In one paragraph

Article in Planta, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Bo ZhangState Key Laboratory of Forage Breeding-by-Design and Utilization; Key Laboratory of Plant Molecular Physiology, Institute of Botany, Chinese Academy of Sciences, No. 20 Nanxincun, Xiangshan, Beijing, 100093, People's Republic of China.
Weitao JiaKey Laboratory of Reservoir Aquatic Environment, Chongqing Institute of Green and Intelligent Technology, Chinese Academy of Sciences, Chongqing, 401122, People's Republic of China.
Kangqi LinState Key Laboratory of Forage Breeding-by-Design and Utilization; Key Laboratory of Plant Molecular Physiology, Institute of Botany, Chinese Academy of Sciences, No. 20 Nanxincun, Xiangshan, Beijing, 100093, People's Republic of China.
Sulian LvState Key Laboratory of Forage Breeding-by-Design and Utilization; Key Laboratory of Plant Molecular Physiology, Institute of Botany, Chinese Academy of Sciences, No. 20 Nanxincun, Xiangshan, Beijing, 100093, People's Republic of China.
Zijing GuoState Key Laboratory of Forage Breeding-by-Design and Utilization; Key Laboratory of Plant Molecular Physiology, Institute of Botany, Chinese Academy of Sciences, No. 20 Nanxincun, Xiangshan, Beijing, 100093, People's Republic of China.
Wenzhu XieState Key Laboratory of Forage Breeding-by-Design and Utilization; Key Laboratory of Plant Molecular Physiology, Institute of Botany, Chinese Academy of Sciences, No. 20 Nanxincun, Xiangshan, Beijing, 100093, People's Republic of China.
Yingjiao HeState Key Laboratory of Forage Breeding-by-Design and Utilization; Key Laboratory of Plant Molecular Physiology, Institute of Botany, Chinese Academy of Sciences, No. 20 Nanxincun, Xiangshan, Beijing, 100093, People's Republic of China.
Yinxin LiState Key Laboratory of Forage Breeding-by-Design and Utilization; Key Laboratory of Plant Molecular Physiology, Institute of Botany, Chinese Academy of Sciences, No. 20 Nanxincun, Xiangshan, Beijing, 100093, People's Republic of China. yxli@ibcas.ac.cn.ORCID http://orcid.org/0000-0001-8962-7034

Funding

the Strategic Priority Research Program of the Chinese Academy of Sciences XDA24010306the Strategic Priority Research Program of the Chinese Academy of Sciences XDA26030201
6 · The paper itself

Abstract

MAIN

conclusionThis study identified a SbABCB11 gene in sorghum that could enhance Cd translocation from roots to shoots, thus increasing Cd accumulation in shoots. Cadmium (Cd) is a widespread soil contaminant threatening human health. As an energy plant, sorghum (Sorghum bicolor (L.) Moench) has great potential in phytoremediation of Cd-polluted soils. ATP-binding cassette (ABC) transporters perform critical roles in transport of Cd. However, there has not yet been a comprehensive analysis of the ABC gene family in sorghum. In this study, 142 ABC genes in sorghum were identified. Transcriptome study showed 41 SbABCs with differential expression patterns under Cd treatment. Candidate gene-based association study for Cd translocation factors identified five significant SNPs inside the annotated gene SbABCB11. Sequence analysis in different haplotypes demonstrated there were multiple long indel variations in the coding region of SbABCB11. Expression study indicated that SbABCB11-Hap3 was upregulated in roots after Cd treatment. Yeast complementary assay proved that SbABCB11 participated in the efflux of Cd, which was further supported by the localization of SbABCB11 on the plasma membrane. Transient suppression of SbABCB11 via antisense oligodeoxyribonucleotide (asODN) method reduced Cd accumulation in the shoots of sorghum by decreasing the release of Cd into the xylem. Our results provide new insights into the potential roles of SbABCs in sorghum. We revealed that SbABCB11 participated in translocation of Cd from roots to shoots, and there were significant variations in the translocation ability among different haplotypes of SbABCB11. These findings will be of help for the molecular breeding of sorghum germplasms suitable for the phytoremediation of Cd-contaminated soils.

Indexed as

ATP-Binding Cassette TransportersCadmiumPlant ProteinsPlant ShootsSorghumBiodegradation, EnvironmentalBiological TransportGene Expression Regulation, PlantHaplotypesMultigene FamilyPlant RootsPolymorphism, Single NucleotideSoil PollutantsATP-Binding Cassette TransportersCadmiumPlant ProteinsSoil PollutantsAsODNCadmium effluxCandidate gene-based associationHaplotype analysisSorghumXylem loading

Identifiers

PMID39979492

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.