Evidence map›Paper›PMID 39980683›Full record

ArticleFrontiers in nutrition2025

Malícia honey (

Maria Luiza Rolim Bezerra, Mirela Gouveia-Nhanca, Maria Letícia da Veiga Dutra, Kamila Sabino Batista, Alana Natalícia Vasconcelos de Araújo, Marcos Dos Santos Lima, Mateus Duarte Ribeiro, Alexandre Sergio Silva, Adriano Francisco Alves, Tatiana Colombo Pimentel and 2 more

Abstract read
In one paragraph

Article in Frontiers in nutrition, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Maria Luiza Rolim BezerraExperimental Nutrition Laboratory-LANEX, Department of Nutrition, Federal University of Paraíba (UFPB), João Pessoa, Brazil.
Mirela Gouveia-NhancaExperimental Nutrition Laboratory-LANEX, Department of Nutrition, Federal University of Paraíba (UFPB), João Pessoa, Brazil.
Maria Letícia da Veiga DutraExperimental Nutrition Laboratory-LANEX, Department of Nutrition, Federal University of Paraíba (UFPB), João Pessoa, Brazil.
Kamila Sabino BatistaSemi Arid National Institute (INSA), Campina Grande, Brazil.
Alana Natalícia Vasconcelos de AraújoExperimental Nutrition Laboratory-LANEX, Department of Nutrition, Federal University of Paraíba (UFPB), João Pessoa, Brazil.
Marcos Dos Santos LimaDepartment of Food Technology, Instituto Federal do Sertão Pernambucano (IFSertãoPE), Petrolina, Brazil.
Mateus Duarte RibeiroLaboratory of Applied Studies in Physical Training to Performance and Health (LETFADS), Department of Physical Education, Federal University of Paraíba (UFPB), João Pessoa, Brazil.
Alexandre Sergio SilvaPost Graduate Program in Nutrition Sciences, Federal University of Paraíba (UFPB), João Pessoa, Brazil.
Adriano Francisco AlvesLaboratory of General Pathology, Department of Physiology and Pathology, Federal University of Paraíba (UFPB), João Pessoa, Brazil.
Tatiana Colombo PimentelInstituto Federal do Paraná (IFPR), Campus Paranavaí, Paranavaí, Brazil.
Marciane MagnaniPost Graduate Program in Nutrition Sciences, Federal University of Paraíba (UFPB), João Pessoa, Brazil.
Jailane de Souza AquinoExperimental Nutrition Laboratory-LANEX, Department of Nutrition, Federal University of Paraíba (UFPB), João Pessoa, Brazil.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background and aims: Obesity is a disease associated with increased oxidative stress in humans and animals, and consumption of antioxidant compounds such as polyphenols can minimise it. These compounds are abundant in malícia ( Methods: Wistar rats (228 ± 14.69 g) were randomly divided into two groups: a healthy group (HG, Results: The administration of malícia honey reduced energy intake and weight gain in the OGH in comparison to the OG. Total antioxidant capacity increased in the brain, liver, and gut in both groups treated with honey compared to respective controls. Lipid peroxidation decreased in the brain, gut, and kidney of the OGH. Both treated groups showed elevated phenolic compound deposition, including catechin, procyanidins, and flavonoids, across all organs. Specifically, the brain in the OGH showed greater procyanidin B2 and gallic acid deposition; the liver showed increased procyanidin B1 and B2, epicatechin, and myricetin concentrations; the gut showed higher procyanidin B2 and kaempferol 3-glucoside concentrations; and the kidneys had increased catechin, procyanidin B1 and B2, and gallic acid deposition compared to the OG. Conclusion: Histologically, the OGH displayed reduced neuronal damage and prevention of hepatic steatosis induced by the cafeteria diet. Malícia honey effectively reduced oxidative stress via modulation of phenolic compounds in the brain, gut, kidney, and liver of cafeteria diet-induced obese rats.

Indexed as

cafeteria dietobesityoxidative stressphenolic compoundsstingless bee honey

Identifiers

PMID39980683
PMCPMC11839446

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.