Evidence map›Paper›PMID 39982207›Full record

ArticleRadiology. Imaging cancer2025

Spatial Radiomic Graphs for Outcome Prediction in Radiation Therapy-treated Head and Neck Squamous Cell Carcinoma Using Pretreatment CT.

Joseph Bae, Kartik Mani, Lukasz Czerwonka, Christopher Vanison, Samuel Ryu, Prateek Prasanna

Abstract read
In one paragraph

Article in Radiology. Imaging cancer, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Joseph BaeDepartment of Biomedical Informatics, 100 Nicolls Rd, Health Science Center Level 3, Rm 043, Stony Brook, NY 11794.ORCID 0000-0002-9440-6655
Kartik ManiDepartment of Radiation Oncology, Stony Brook University, Stony Brook, NY.
Lukasz CzerwonkaDepartment of Otolaryngology-Head and Neck Surgery, Stony Brook University, Stony Brook, NY.
Christopher VanisonDepartment of Otolaryngology-Head and Neck Surgery, Stony Brook University, Stony Brook, NY.ORCID 0009-0006-3075-5430
Samuel RyuDepartment of Radiation Oncology, Stony Brook University, Stony Brook, NY.
Prateek PrasannaDepartment of Biomedical Informatics, 100 Nicolls Rd, Health Science Center Level 3, Rm 043, Stony Brook, NY 11794.ORCID 0000-0002-3068-3573

Funding

MEDICAL SCIENTIST TRAINING PROGRAMT32GM008444 · NIGMS · STATE UNIVERSITY NEW YORK STONY BROOK · PI FROHMAN, MICHAEL A. · 1992 to 2024
$12.6M
SCH: Topological Methods for Breast Tissue QuantificationR01CA297843 · NCI · STATE UNIVERSITY NEW YORK STONY BROOK · PI Chao Chen, Prateek Prasanna · 2024 to 2026
$900k
IMAT-ITCR Collaboration: Combining FIBI and topological data analysis: Synergistic approaches for tumor structural microenvironment explorationR21CA258493 · NCI · STATE UNIVERSITY NEW YORK STONY BROOK · PI CHEN, CHAO, PRASANNA, PRATEEK · 2022 to 2023
$467k
NCI NIH HHS R01 CA297843NCI NIH HHS R21 CA258493NIGMS NIH HHS T32 GM008444
6 · The paper itself

Abstract

Purpose To develop a radiomic graph framework, RadGraph, for spatial analysis of pretreatment CT images to improve prediction of local-regional recurrence (LR) and distant metastasis (DM) in head and neck squamous cell carcinoma (HNSCC). Materials and Methods This retrospective study included four public pre-radiotherapy treatment CT datasets of patients with HNSCC obtained from The Cancer Imaging Archive (images collected between 2003 and 2018). Computational graphs and graph attention deep learning methods were leveraged to holistically model multiple regions in the head and neck anatomy. Clinical features, including age, sex, and human papillomavirus infection status, were collected for a baseline model. Model performance in predicting LR and DM was evaluated via area under the receiver operating characteristic curve (AUC) and qualitative interpretation of model attention. Results A total of 3434 patients (61 years ± 11 [SD], 2774 male) were divided into training (

Indexed as

Head and Neck NeoplasmsSquamous Cell Carcinoma of Head and NeckTomography, X-Ray ComputedAgedDeep LearningFemaleHumansMaleMiddle AgedNeoplasm Recurrence, LocalRadiomicsRetrospective StudiesComputer Applications–General (Informatics)CTDeep LearningHead and Neck Squamous Cell CarcinomaHead/NeckInformaticsLocoregional RecurrenceNeural NetworksRadiation TherapyRadiomicsRadiotherapyTumor Response

Identifiers

PMID39982207
PMCPMC11966549

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.