Evidence map›Paper›PMID 39984952›Full record

ArticleRespiratory research2025

Impacts of vaping and marijuana use on airway health as determined by exhaled breath condensate (EBC).

Dante E Rojas, Mitchell M McCartney, Eva Borras, Tristan L Hicks, Tiffany T Lam, Nicholas J Kenyon, Cristina E Davis

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Respiratory research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Harnessing breath biomarkers for pneumonia diagnosis and prognosis.Expert review of respiratory medicine · 2026
    Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Dante E Rojas *Mechanical and Aerospace Engineering, University of California, Davis, Davis, CA, USA.
Mitchell M McCartney *Mechanical and Aerospace Engineering, University of California, Davis, Davis, CA, USA.
Eva BorrasMechanical and Aerospace Engineering, University of California, Davis, Davis, CA, USA.
Tristan L HicksMechanical and Aerospace Engineering, University of California, Davis, Davis, CA, USA.
Tiffany T LamMechanical and Aerospace Engineering, University of California, Davis, Davis, CA, USA.
Nicholas J KenyonUC Davis Lung Center, University of California, Davis, CA, USA.
Cristina E DavisMechanical and Aerospace Engineering, University of California, Davis, Davis, CA, USA. cedavis@ucdavis.edu.

Funding

UC Davis Environmental Health Sciences Core CenterP30ES023513 · NIEHS · UNIVERSITY OF CALIFORNIA AT DAVIS · PI Irva Hertz-Picciotto · 2015 to 2026
$26.0M
Monitoring of disease-induced skin VOC patterns from handheld and wearable chemical sensorsU01TR004083 · NCATS · UNIVERSITY OF CALIFORNIA AT DAVIS · PI CRISTINA ELIZABETH DAVIS, Nicholas J. KENYON · 2022 to 2026
$5.9M
BLRD VA I01 BX004965NCATS NIH HHS U01 TR004083NCATS NIH HHS U01-TR004083NIEHS NIH HHS P30 ES023513NIH HHS P30-ES023513Office of the President, University of California R02CP7431University of California Tobacco-Related Disease Research Program T31IR1614U.S. Department of Energy DE-NA0003525U.S. Department of Veterans Affairs I01-BX004965
6 · The paper itself

Abstract

Across the United States, there is increased use of cannabis products and electronic delivery systems for cannabis products and nicotine, yet little is known about their impacts on lung health. We analyzed exhaled breath condensate of 254 participants who were non-users and users who used cannabis and tobacco products. The 132 participants reported using a product ("users") were distributed into cohorts of tobacco products and cannabis products, with some participants following into multiple cohorts. Targeted analysis of inflammatory oxylipins found up-regulation among persons using tobacco products, while cannabis users had concentrations closer to nonusers, and often down-regulated. Untargeted screening of 403 significant metabolites found tobacco users had similar breath profiles, and that cannabis users had a similar profile that was closer to the profile of nonusers. Metabolites were significantly higher in breath of people using combustion products (tobacco and cannabis) relative to nonusers, and significantly lower in e-device users (nicotine and THC). Our work demonstrates the relative impact of e-delivery systems and cannabis products compared to traditional cigarette smoking on lung metabolic profiles.

Indexed as

ExhalationLungMarijuana SmokingMarijuana UseVapingAdultBreath TestsCohort StudiesElectronic Nicotine Delivery SystemsFemaleHumansMaleMiddle AgedYoung Adult

Identifiers

PMID39984952
PMCPMC11846476

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.