ArticleLa Radiologia medica2025
Pancreatic changes in patients with visceral fat obesity: an evaluation with contrast-enhanced dual-energy computed tomography with automated three-dimensional volumetry.
Article in La Radiologia medica, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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Who cites it
2 citing papers in PubMed.
- Association of BCAAs/BCKAs with pancreatic steatosis in patients with type 2 diabetes mellitus: A cross-sectional study.Journal of diabetes investigation · 2026Article
- Radiological Assessment After Pancreaticoduodenectomy for a Precision Approach to Managing Complications: A Narrative Review.Journal of personalized medicine · 2025Review
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10 authors.
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Abstract
purposeTo investigate pancreatic changes associated with visceral fat obesity (VFO) and their clinical relevance using contrast-enhanced dual-energy CT (DE-CT) with automated 3D volumetry.
methodsThis retrospective study included patients who underwent triple-phase contrast-enhanced dynamic abdominal DE-CT. The patients were divided into two groups based on the measured visceral fat area: the VFO group (≥ 100 cm
resultsIn total, 119 patients were evaluated (mean age, 67.6 ± 12.9 years old; 80 men). The extracellular volume fraction calculated from iodine maps (ECV-ID) (r = -0.683, p < 0.001) was most strongly associated with the visceral fat area, followed by the fat volume fraction (FVF) of the pancreas (r = 0.582, p < 0.001) with a statistically moderate correlation. The pancreatic volume and FVF of the pancreas were significantly higher in the VFO group than in the non-VFO group (volume: 84.9 ± 22.9 vs. 76.5 ± 25.8, p = 0.025, FVF: 15.5 ± 7.7 vs. 8.7 ± 9.5, p < 0.001). Conversely, the pancreatic CT attenuation value on unenhanced CT (19.9 ± 12.0 vs. 29.6 ± 13.8, p < 0.001), pancreatic iodine concentration in the equilibrium phase (EP) (18.4 ± 5.7 vs. 19.8 ± 4.7, p = 0.003), contrast enhancement (CE) value of pancreas (32.2 ± 5.3 vs. 34.5 ± 8.5, p = 0.005), and ECV-ID (26.7 ± 5.4 vs. 34.1 ± 7.4, p < 0.001) in the VFO group were significantly lower than those in the non-VFO group.
conclusionAn increase in the pancreatic volume and FVF of the pancreas, as well as a reduction in the ECV fraction and the CE value in EP of the pancreas measured by automated 3D DE-CT volumetry, were the characteristic pancreatic changes in patients with VFO.
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