Evidence mapPaperPMID 39988639Full record

ReviewPlant foods for human nutrition (Dordrecht, Netherlands)2025

Mycochemistry, Traditional Uses, and Nutraceutical Potential of Laricifomes officinalis: A Biotechnological and Pharmacological Perspective.

Yusufjon Gafforov, Milena Rašeta, Oksana Mykchaylova, Sylvie Rapior, Maja Karaman, Jovana Mišković, Şule İnci, Manzura Yarasheva, Arshad Mehmood Abbasi, Soumya Ghosh

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Review in Plant foods for human nutrition (Dordrecht, Netherlands), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Yusufjon GafforovCentral Asian Center for Development Studies, New Uzbekistan University, Tashkent, 100007, Uzbekistan. y.gafforov@newuu.uz.
Milena RašetaDepartment of Chemistry, Biochemistry and Environmental Protection, Faculty of Sciences, University of Novi Sad, Novi Sad, 21000, Serbia.
Oksana MykchaylovaDepartment of Mycology, M. G. Kholodny Institute of Botany National Academy of Science of Ukraine, Kyiv, 01601, Ukraine.
Sylvie RapiorCEFE, Univ Montpellier, CNRS, EPHE, IRD, Natural Substances and Chemical Mediation Team, 34093, Montpellier cedex 5, France.
Maja KaramanDepartment of Biology and Ecology, Faculty of Sciences, University of Novi Sad, Novi Sad, 21000, Serbia.
Jovana MiškovićDepartment of Biology and Ecology, Faculty of Sciences, University of Novi Sad, Novi Sad, 21000, Serbia.
Şule İnciHealth Services Vocational School, İstanbul Rumeli University, İstanbul, Turkey.
Manzura YarashevaMicrobiology Laboratory, Navruz International Corp. LLC, Salar settlement, Kibray, 111219, Uzbekistan.
Arshad Mehmood AbbasiDepartment of Environmental Sciences, COMSATS University Islamabad, Abbottabad Campus, Islamabad, 22060, Pakistan.
Soumya GhoshNatural and Medical Sciences Research Center, University of Nizwa, Nizwa , 616, Oman.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Laricifomes officinalis is a medicinal wood-inhabiting fungus renowned for its health benefits, particularly in traditional European medicine for the prevention and treatment of pulmonary conditions such as asthma, pneumonia, and tuberculosis. Beyond its therapeutic applications, L. officinalis plays an important ecological role by contributing to nutrient cycling in forest ecosystems. This review provides a comprehensive analysis of the current literature on L. officinalis, focusing on its phytochemical composition, traditional uses, pharmacological potential, and conservation status. The species is a rich source of bioactive compounds, including coumarin derivatives, indole compounds, phenolic compounds, polysaccharides, terpenoids and sterols, which exhibit a wide array of biological activities, such as antibacterial, anticancer, antifungal, anti-inflammatory, antioxidant, and antiviral effects. Drawing on extensive searches in scientific databases including Google Scholar, PubMed, Scopus, and Web of Science, this review examines the distribution, ecological significance, taxonomy, and pharmacological applications of L. officinalis. Given the growing threats of overexploitation and habitat loss, the conservation of L. officinalis is crucial. This review discusses various sustainable cultivation strategies, including establishing culture collections and regulating biosynthetic activity through LED and laser light techniques, show potential for preserving and enhancing the production of its bioactive compounds. Despite recent advances, further research is required to better understand the pharmacological efficacy and safety of L. officinalis, thereby unlocking its full medicinal potential for future therapeutic applications. This review underscores the necessity of integrating ecological conservation with pharmaceutical research, highlighting the dual importance of L. officinalis in natural ecosystems and therapeutic applications.

Indexed as

Dietary SupplementsBiotechnologyHumansMedicine, TraditionalPhytochemicalsPhytochemicalsBioactivityEthnomedicineFungal metabolitesHealth benefitsMedicinal macrofungiSustainable cultivation

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.