Evidence mapPaperPMID 39988813Full record

ArticleOrganogenesis2025

Correlation of MicroRNA-31 with Endometrial Receptivity in Patients with Repeated Implantation Failure of

Yan Tan, Bijun Du, Xixi Chen, Minhong Chen

Abstract read
In one paragraph

Article in Organogenesis, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Review
  3. The Role of miRNA in Endometriosis-Related Infertility-An Update.International journal of molecular sciences · 2025
    Review
  4. Review
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Yan TanDepartment of Obstetrics, Guangzhou Red Cross Hospital, Guangzhou, Guangdong, China.
Bijun DuDepartment of Obstetrics, The Second Affiliated Hospital of Guangzhou Medical University, Guangzhou, Guangdong, China.
Xixi ChenDepartment of Reproductive Medicine Centre, Jiangmen Central Hospital, Jiangmen, China.
Minhong ChenDepartment of Obstetrics, First Dongguan Affiliated Hospital, Guangzhou Medical University, Dongguan, Guangdong, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThis trial probed the correlation between miR-31 expression and endometrial receptivity (ER) in patients with repeated implantation failure (RIF) of in vitro fertilization and embryo transfer (IVF-ET).

methodsA retrospective study of 80 infertility patients who underwent IVF-ET assisted conception treatment were divided into RIF group and normal pregnancy group (control group) according to the pregnancy outcome after embryo transfer. General information of both groups was collected. Endometrial tissues were collected in the middle luteal phase of the menstrual cycle before IVF-ET. miR-31 levels in endometrial tissues were measured, and endometrial tolerance indicator pulsatility index (PI), resistance index (RI), and endometrial thickness (Em) were detected. The correlation between endometrial miR-31 levels and ER indices was evaluated by Pearson method. ROC curves were utilized to analyze the efficacy of miR-31 in predicting RIF occurrence. The influencing factors of RIF were analyzed by binary Logistic regression.

resultsRIF patients had increased miR-31 expression level and endometrial tolerance indicator PI, and RI while decreased Em (

conclusionmiR-31 in RIF patients is positively correlated with PI and RI, and negatively correlated with Em.

Indexed as

Embryo ImplantationEmbryo TransferEndometriumFertilization in VitroMicroRNAsAdultFemaleHumansPregnancyRetrospective StudiesTreatment FailureMicroRNAsMIRN31 microRNA, humanEndometrial receptivityendometrial thicknessin vitro fertilization-embryo transferMicroRNA-31pulsatility indexrepeated implantation failureresistance index

Identifiers

PMID39988813
PMCPMC11853553

What Socratic holds

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.