Evidence map›Paper›PMID 39989960›Full record

ArticleResearch square2025

Remodeling of extracellular matrix collagen IV by MIG-6/papilin regulates neuronal architecture.

Malika Nadour, Robert I Valette Reveno Leatis, Marie Biard, Noémie Frébault, Lise Rivollet, Philippe St-Louis, Cassandra R Blanchette, Andrea Thackeray, Paola Perrat, Carlo Bevilacqua and 5 more

Abstract readPreprint
In one paragraph

Article in Research square, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Malika NadourUniversité du Québec à Montréal, Department of Biological Sciences, Montreal, QC, Canada.
Robert I Valette Reveno LeatisUniversité du Québec à Montréal, Department of Biological Sciences, Montreal, QC, Canada.
Marie BiardUniversité du Québec à Montréal, Department of Biological Sciences, Montreal, QC, Canada.
Noémie FrébaultUniversité du Québec à Montréal, Department of Biological Sciences, Montreal, QC, Canada.
Lise RivolletUniversité du Québec à Montréal, Department of Biological Sciences, Montreal, QC, Canada.
Philippe St-LouisUniversité du Québec à Montréal, Department of Biological Sciences, Montreal, QC, Canada.
Cassandra R BlanchetteUniversity of Massachusetts Chan Medical School, Department of Neurobiology, MA, USA.
Andrea ThackerayUniversity of Massachusetts Chan Medical School, Department of Neurobiology, MA, USA.
Paola PerratUniversity of Massachusetts Chan Medical School, Department of Neurobiology, MA, USA.
Carlo BevilacquaCell Biology and Biophysics Unit, European Molecular Biology Laboratory, Heidelberg, Germany.ORCID 0000-0001-9084-0641
Robert PrevedelCell Biology and Biophysics Unit, European Molecular Biology Laboratory, Heidelberg, Germany.ORCID 0000-0003-3366-4703
Laurent CappadociaCentre d'Excellence en Recherche sur les Maladies Orphelines - Fondation Courtois (CERMO-FC Research Center), Université du Québec à Montréal, Montreal, QC, Canada.ORCID 0000-0001-7348-1982
Georgia RaptiDevelopmental Biology Unit, European Molecular Biology Laboratory, Heidelberg, Germany.ORCID 0000-0003-4836-8640
Maria DoitsidouUniversity of Edinburgh, Centre for Discovery Brain Sciences, Edinburgh, Scotland.ORCID 0000-0002-2358-9810
Claire Y BénardUniversité du Québec à Montréal, Department of Biological Sciences, Montreal, QC, Canada.ORCID 0000-0002-1919-1877

Funding

Center for C elegans AnatomyR24OD010943 · OD · ALBERT EINSTEIN COLLEGE OF MEDICINE, INC · PI DAVID H. HALL, Nathan Schroeder · 2012 to 2026
$9.6M
Enhancing and expanding the CGC Strain CollectionP40OD010440 · OD · UNIVERSITY OF MINNESOTA · PI Aric L Daul, Ann E. Rougvie · 2012 to 2026
$7.5M
Molecular mechanisms of nervous system protectionR01AG041870 · NIA · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI ALKEMA, MARK · 2012 to 2016
$1.7M
NIA NIH HHS R01 AG041870NIH HHS P40 OD010440NIH HHS R24 OD010943
6 · The paper itself

Abstract

Neuronal architecture established embryonically must persist lifelong to ensure normal brain function. However, little is understood about the mechanisms behind the long-term maintenance of neuronal organization. To uncover maintenance mechanisms, we performed a suppressor screen in

Indexed as

collagen IVextracellular matrixMIG-6neuronal maintenancePapilin

Identifiers

PMID39989960
PMCPMC11844652

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.