Evidence map›Paper›PMID 39990449›Full record

ArticlebioRxiv : the preprint server for biology2025

Cystinosin is involved in Na

Veenita Khare, Jean-Claude Farre, Celine Rocca, Mouad Ait Kbaich, Cynthia Tang, Xuan Ma, Kavya Beiderman, Ioli Mathur, Rafael A Badell-Grau, Anusha Sivakumar and 3 more

Abstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Veenita KhareDepartment of Pediatrics, University of California, San Diego, La Jolla, California, USA.
Jean-Claude FarreDivision of Biological Sciences, University of California, San Diego, La Jolla, California, USA.
Celine RoccaDepartment of Pediatrics, University of California, San Diego, La Jolla, California, USA.
Mouad Ait KbaichDepartment of Molecular Medicine and Molecular and Cellular Biology, The Scripps Research Institute, La Jolla, California, USA.
Cynthia TangDepartment of Pediatrics, University of California, San Diego, La Jolla, California, USA.
Xuan MaDepartment of Pediatrics, University of California, San Diego, La Jolla, California, USA.
Kavya BeidermanDepartment of Pediatrics, University of California, San Diego, La Jolla, California, USA.ORCID 0009-0006-0043-4492
Ioli MathurDepartment of Pediatrics, University of California, San Diego, La Jolla, California, USA.ORCID 0009-0001-8575-8149
Rafael A Badell-GrauDepartment of Pediatrics, University of California, San Diego, La Jolla, California, USA.ORCID 0000-0001-7640-822X
Anusha SivakumarDepartment of Pediatrics, University of California, San Diego, La Jolla, California, USA.
Rola ChenDepartment of Pediatrics, University of California, San Diego, La Jolla, California, USA.
Sergio D CatzDepartment of Molecular Medicine and Molecular and Cellular Biology, The Scripps Research Institute, La Jolla, California, USA.
Stephanie CherquiDepartment of Pediatrics, University of California, San Diego, La Jolla, California, USA.ORCID 0000-0003-0677-8967

Funding

U of Calif, San Diego Neuroscience Microscopy ImagingP30NS047101 · NINDS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Binhai Zheng · 2003 to 2021
$2.9M
Neutrophil Survival and Demise During Inflammatory StatesP01HL152958 · SCRIPPS RESEARCH INSTITUTE, THE · 2025 to 2025
$2.4M
Molecular and Cellular Mechanisms of the Lysosomal Storage Disease CystinosisR01DK110162 · SCRIPPS RESEARCH INSTITUTE, THE · 2025 to 2025
$741k
Microgial contribution and therapeutic potential in Friedreich's ataxiaR01NS135162 · UNIVERSITY OF CALIFORNIA, SAN DIEGO · 2025 to 2025
$585k
Understanding the mechanism of rescue of Alzheimers disease by hematopoietic stem cell transplantationR01AG086443 · UNIVERSITY OF CALIFORNIA, SAN DIEGO · 2025 to 2025
$387k
NHLBI NIH HHS P01 HL152958NIA NIH HHS R01 AG086443NIDDK NIH HHS R01 DK110162NIH HHS S10 OD030417NINDS NIH HHS P30 NS047101NINDS NIH HHS R01 NS108965NINDS NIH HHS R01 NS135162
6 · The paper itself

Abstract

Cystinosis is a systemic lysosomal storage disease resulting from a defective

Indexed as

cystinosincystinosishematopoietic stem cellsNa+/H+ Exchanger 3proximal tubular cellsrenal Fanconi syndrome

Identifiers

PMID39990449
PMCPMC11844504

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.