Evidence map›Paper›PMID 39995406›Full record

ArticleFood chemistry: X2025

Grape stems as sources of tryptophan and selenium: Functional properties and antioxidant potential.

Raquel Fernandes, Concepción Medrano-Padial, Rui Dias-Costa, Raúl Domínguez-Perles, Cláudia Botelho, Rúben Fernandes, Ana Novo Barros

Abstract read
In one paragraph

Article in Food chemistry: X, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Raquel FernandesCentre for the Research and Technology of Agro-Environmental and Biological Sciences, CITAB, Inov4Agro, Universidade Trás-os-Montes e Alto Douro, UTAD, Quinta de Prados, 5000-801 Vila Real, Portugal.
Concepción Medrano-PadialPhytochemistry and Healthy Foods Lab (LabFAS), CEBAS-CSIC, Campus Universitario de Espinardo, Edif. 25, 30100 Murcia, Spain.
Rui Dias-CostaCentre for the Research and Technology of Agro-Environmental and Biological Sciences, CITAB, Inov4Agro, Universidade Trás-os-Montes e Alto Douro, UTAD, Quinta de Prados, 5000-801 Vila Real, Portugal.
Raúl Domínguez-PerlesPhytochemistry and Healthy Foods Lab (LabFAS), CEBAS-CSIC, Campus Universitario de Espinardo, Edif. 25, 30100 Murcia, Spain.
Cláudia BotelhoCEB-Centre of Biological Engineering, University of Minho, 4710-057 Braga, Portugal.
Rúben FernandesCECLIN, Centro de Estudos Clínicos, Hospital Escola Fernando Pessoa, 4420-096 Gondomar, Portugal.
Ana Novo BarrosCentre for the Research and Technology of Agro-Environmental and Biological Sciences, CITAB, Inov4Agro, Universidade Trás-os-Montes e Alto Douro, UTAD, Quinta de Prados, 5000-801 Vila Real, Portugal.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The Douro Demarcated Region's winery industry produces million tonnes of by-products annually, making their reuse essential to minimize environmental impact. Grape stems, rich in bioactive compounds and nutrients, have demonstrated potential health benefits. This study analysed four red grape stems from the Douro region to assess their nutritional value and potential health benefit. Tryptophan, selenium, and phenolic compounds, which regulate cognitive functions, protein and enzyme synthesis, and antioxidant processes, were analysed. Among the varieties, Touriga Nacional exhibited the highest levels of selenium, phenolics, and antioxidant capacity. Tinta Amarela and Touriga Nacional exhibited higher tryptophan levels. Moreover, proanthocyanidins, phenolic acids, flavonols, and anthocyanins were identified in all the varieties analysed. These findings highlight grape stems, particularly Touriga Nacional, as valuable sources of amino acids and bioactive compounds, offering potential in mood regulation, protein synthesis, and antioxidant defence. This research emphasizes their value to reduce waste, generating revenue, and promoting environmental sustainability.

Indexed as

Grape stemsHealth potentialNutrition valorisationOne healthPhenolic profile

Identifiers

PMID39995406
PMCPMC11848443

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.