ReviewBiosensors2025
Development of Neurodegenerative Disease Diagnosis and Monitoring from Traditional to Digital Biomarkers.
Review in Biosensors, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed.
- Effects of immersive virtual reality and adaptive cognitive training on cognition and function in parkinson's disease mild cognitive impairment: a randomized clinical trial.Scientific reports · 2026Trial
- Demographic Shortcuts Account for Most of the Apparent Accuracy of Four-Class Gait-Based Differential Diagnosis in Neurodegenerative Disease: An Interpretability-Driven Audit of Machine Learning on a Public Gait Benchmark.Bioengineering (Basel, Switzerland) · 2026Article
- Entropy-Based Analysis of Olfactory EEG as a Candidate Biomarker for Early Mild Cognitive Impairment Detection: A Proof-of-Concept Study.Biosensors · 2026Article
- Advancing Neurorehabilitation and Recovery Through Human Movement Quantification via Wearable Sensing.Neurorehabilitation and neural repair · 2026Article
- Review
- Handwriting as a Biomarker for Early Detection of Parkinson's and Alzheimer's Diseases: A Comprehensive Guide for Researchers.Sensors (Basel, Switzerland) · 2026Review
- Bidirectionality and the application of the integrated neurocognitive model of technological cognition to late life cognitive health.Cognitive neuroscience · 2026Article
- Network Biology of Alzheimer's Disease and Related Neurodegenerative Disorders: Molecular Mechanisms and Therapeutic Strategies.Biomolecules · 2026Review
- From phenotype to biology: a multi-modal roadmap of biofluid, tissue, imaging, and digital biomarkers in Parkinson's disease.Translational neurodegeneration · 2026Review
- Application of Deep Multi-Scale Representation Learning Based on Eye-Tracking and Facial Expression Data in Cognitive Decline Assessment.Sensors (Basel, Switzerland) · 2026Article
- Advanced Research in Neuroprotection.Biomedicines · 2026Article
- Enhancing Early Diagnosis: Multimodal AI Approaches for Neurodegenerative Diseases.Journal of biotechnology and biomedicine · 2026Article
- An integrative neurogenomics workflow for precision medicine in neurodegenerative disorders.Frontiers in dementia · 2026Article
- Mechanistic Insights into the Metabolic Pathways and Neuroprotective Potential of Pentacyclic Triterpenoids: In-Depth Analysis of Betulin, Betulinic, and Ursolic Acids.Biomolecules · 2025Review
- Comparing deep learning CNN method with traditional MRI-based hippocampal segmentation and volumetry for early Alzheimer's disease diagnosis across diverse populations.Scientific reports · 2025Article
- From Innovation to Integration: Bridging the Gap Between IoMT Technologies and Real-World Health Management Systems.Sensors (Basel, Switzerland) · 2025Article
- Digital Twin Cognition: AI-Biomarker Integration in Biomimetic Neuropsychology.Biomimetics (Basel, Switzerland) · 2025Review
- Assessing the Role of EEG Biosignal Preprocessing to Enhance Multiscale Fuzzy Entropy in Alzheimer's Disease Detection.Biosensors · 2025Article
- Interplay of Neuroinflammation and Gut Microbiota Dysbiosis in Alzheimer's Disease Using Diffusion Kurtosis Imaging Biomarker in 3 × Tg-AD Mouse Models.ACS chemical neuroscience · 2025Article
- Global research landscape, hotspots, and emerging trends of digital biomarkers: A bibliometric analysis.Digital healthArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
Abstract
Monitoring and assessing the progression of symptoms in neurodegenerative diseases, including Alzheimer's and Parkinson's disease, are critical for improving patient outcomes. Traditional biomarkers, such as cerebrospinal fluid analysis and brain imaging, are widely used to investigate the underlying mechanisms of disease and enable early diagnosis. In contrast, digital biomarkers derived from phenotypic changes-such as EEG, eye movement, gait, and speech analysis-offer a noninvasive and accessible alternative. Leveraging portable and widely available devices, such as smartphones and wearable sensors, digital biomarkers are emerging as a promising tool for ND diagnosis and monitoring. This review highlights the comprehensive developments in digital biomarkers, emphasizing their unique advantages and integration potential alongside traditional biomarkers.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.