Evidence map›Paper›PMID 39997018›Full record

ArticleBiosensors2025

Signal Differentiation of Moving Magnetic Nanoparticles for Enhanced Biodetection and Diagnostics.

Kee Young Hwang, Dakota Brown, Supun B Attanayake, Dan Luu, Minh Dang Nguyen, T Randall Lee, Manh-Huong Phan

Abstract read
In one paragraph

Article in Biosensors, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Article
  3. Fine-Tuning the Superparamagnetic Properties of FeO@FeACS applied materials & interfaces · 2025
    Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Kee Young HwangLaboratory for Advanced Materials and Sensors, Department of Physics, University of South Florida, Tampa, FL 33620, USA.
Dakota BrownLaboratory for Advanced Materials and Sensors, Department of Physics, University of South Florida, Tampa, FL 33620, USA.
Supun B AttanayakeLaboratory for Advanced Materials and Sensors, Department of Physics, University of South Florida, Tampa, FL 33620, USA.ORCID 0000-0003-0799-7889
Dan LuuLaboratory for Advanced Materials and Sensors, Department of Physics, University of South Florida, Tampa, FL 33620, USA.ORCID 0009-0002-3949-1794
Minh Dang NguyenDepartment of Chemistry and the Texas Center for Superconductivity, University of Houston, Houston, TX 77204, USA.ORCID 0000-0002-2569-8279
T Randall LeeDepartment of Chemistry and the Texas Center for Superconductivity, University of Houston, Houston, TX 77204, USA.ORCID 0000-0001-9584-8861
Manh-Huong PhanLaboratory for Advanced Materials and Sensors, Department of Physics, University of South Florida, Tampa, FL 33620, USA.

Funding

Department of Energy DE-FG02-07ER46438
6 · The paper itself

Abstract

Magnetic nanoparticles are extensively utilized as markers/signal labelling in various biomedical applications. Detecting and distinguishing magnetic signals from similarly sized moving magnetic nanoparticles in microfluidic systems is crucial yet challenging for biosensing. In this study, we have developed an original method to detect and differentiate magnetic signals from moving superparamagnetic (SPM) and ferrimagnetic (FM) nanoparticles of comparable sizes. Our approach utilizes a highly sensitive magnetic-coil-based sensor that harnesses the combined effects of giant magnetoimpedance (GMI) and an LC-resonance circuit, offering performance superior to that of conventional GMI sensors. Iron oxide nanoparticles, which have similar particle sizes but differing coercivities (zero for SPM and non-zero for FM) or similar zero coercivities but differing particle sizes, flow through the magnetic coil at controlled velocities. Their distinct effects are analyzed through changes in the complex impedance of the sensing system. Our findings provide a unique pathway for utilizing SPM and FM nanoparticles as innovative magnetic markers to identify specific biological entities, thereby expanding their potential applications.

Indexed as

Biosensing TechniquesMagnetic Iron Oxide NanoparticlesMagnetite NanoparticlesMagnetite Nanoparticlesbiosensingmagnetic biosensormagnetic markersmagnetic nanoparticles

Identifiers

PMID39997018
PMCPMC11852982

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.