Evidence map›Paper›PMID 39997148›Full record

ReviewBiomimetics (Basel, Switzerland)2025

From Stents to Smart Implants Employing Biomimetic Materials: The Impact of 4D Printing on Modern Healthcare.

Antreas Kantaros, Florian Ion Tiberiu Petrescu, Theodore Ganetsos

Abstract readReview
In one paragraph

Review in Biomimetics (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Antreas KantarosDepartment of Industrial Design and Production Engineering, University of West Attica, 12244 Athens, Greece.ORCID 0000-0001-7927-1468
Florian Ion Tiberiu Petrescu"Theory of Mechanisms and Robots" Department, Faculty of Industrial Engineering and Robotics, National University of Science and Technology Polytechnic Bucharest, 060042 Bucharest, Romania.ORCID 0000-0003-1627-5159
Theodore GanetsosDepartment of Industrial Design and Production Engineering, University of West Attica, 12244 Athens, Greece.ORCID 0000-0003-2081-4960

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The sector of 4D printing represents a new frontier in additive manufacturing that allows for a material's capability to adapt and respond to various stimuli, such as thermal transitions, humidity, and pH levels. The adaptability of such a material has great potential in healthcare applications, especially in designing personalized and responsive medical devices. This article looks into the revolutionary potential of healthcare applications of 4D printing, referencing applications in self-repairable implants, smart stents, personalized drug delivery systems, and response-based prosthetic devices. The advances in 3D printing have created a platform for such innovations to take place, while the material properties unique to 4D printing allow new methods of tackling existing health issues. However, the large-scale application of 4D printing in medicine is currently hampered by material limitations, regulation challenges, and financial challenges. In spite of these challenges, ongoing advances in technologies, combined with artificial intelligence and machine learning, provide the potential to surpass such challenges, hence improving the precision, efficacy, and personalization of medical devices. This work outlines existing applications, looks at potential areas of application in the future, and analyzes potential applications of 4D printing contributing to healthcare, recognizing challenges that need to be overcome in order to unlock its full potential.

Indexed as

4D printingadaptive prostheticsartificial intelligencebioprintinghealthcarematerial innovationmedical devicespersonalized drug deliveryself-healing implantssmart stents

Identifiers

PMID39997148
PMCPMC11853600

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.