Evidence map›Paper›PMID 39997665›Full record

ArticleMembranes2025

Electrospun Collagen-Coated Nanofiber Membranes Functionalized with Silver Nanoparticles for Advanced Wound Healing Applications.

Martin Iurilli, Davide Porrelli, Gianluca Turco, Cristina Lagatolla, Alvise Camurri Piloni, Barbara Medagli, Vanessa Nicolin, Giovanni Papa

Abstract read
In one paragraph

Article in Membranes, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Article
  2. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Martin IurilliPlastic and Reconstructive Surgery Unit, Cattinara Hospital, Strada di Fiume, 447, 34149 Trieste, Italy.ORCID 0009-0007-4634-2582
Davide PorrelliDepartment of Life Sciences, University of Trieste, Via Alexander Fleming 31/B, 34127 Trieste, Italy.ORCID 0000-0002-6437-7646
Gianluca TurcoClinical Department of Medical, Surgical and Health Sciences, University of Trieste, Piazza dell'Ospitale 1, 34129 Trieste, Italy.ORCID 0000-0001-5699-2131
Cristina LagatollaDepartment of Life Sciences, University of Trieste, Via Alexander Fleming 22, 34127 Trieste, Italy.ORCID 0000-0001-5739-6761
Alvise Camurri PiloniClinical Department of Medical, Surgical and Health Sciences, University of Trieste, Piazza dell'Ospitale 1, 34129 Trieste, Italy.ORCID 0000-0002-7428-2085
Barbara MedagliClinical Department of Medical, Surgical and Health Sciences, University of Trieste, Piazza dell'Ospitale 1, 34129 Trieste, Italy.
Vanessa NicolinClinical Department of Medical, Surgical and Health Sciences, University of Trieste, Piazza dell'Ospitale 1, 34129 Trieste, Italy.
Giovanni PapaPlastic and Reconstructive Surgery Unit, Cattinara Hospital, Strada di Fiume, 447, 34149 Trieste, Italy.ORCID 0000-0003-4676-2775

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Complex wounds pose a significant healthcare challenge due to their susceptibility to infections and delayed healing. This study focuses on developing electrospun polycaprolactone (PCL) nanofiber membranes coated with Type I collagen derived from bovine skin and functionalized with silver nanoparticles (AgNPs) to address these issues. The collagen coating enhances biocompatibility, while AgNPs synthesized through chemical reduction with sodium citrate provide broad-spectrum antimicrobial properties. The physical properties of the membranes were characterized using scanning electron microscopy (SEM) and atomic force microscopy (AFM). Results showed the formation of nanofibers without defects and the uniform distribution of AgNPs. A swelling test and contact angle measurements confirmed that the membranes provided an optimal environment for wound healing. In vitro biological assays with murine 3T3 fibroblasts revealed statistically significant (

Indexed as

antibacterialbiocompatibilitycollagenelectrospinningnanofiberspolycaprolactonesilver nanoparticleswound healing

Identifiers

PMID39997665
PMCPMC11857158

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.