Evidence map›Paper›PMID 40000027›Full record

Observational studyBMJ open diabetes research & care2025

Clinical phenotyping of people living with type 1 diabetes according to their levels of diabetes-related distress: results from the SFDT1 cohort.

Dulce Canha, Gloria Aguayo, Emmanuel Cosson, Patricia Vaduva, Eric Renard, Fawaz Alzaid, Fabrice Bonnet, Samy Hadjadj, Louis Potier, Bruno Vergès and 6 more

Registry-linked trialAbstract readObservational Study
In one paragraph

Observational study in BMJ open diabetes research & care, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04657783 (French National Cohort of People With Type 1 Diabètes), which is not on this map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04657783 recruitingnot on this map

French National Cohort of People With Type 1 Diabètes: the SFDT1 Study

Typeobservational_patient_registrySponsorFondation Francophone pour la Recherche sur le DiabeteRan2020 to 2035Enrolled15,000ConditionsDiabetes Mellitus, Type 1, Cardiovascular Diseases, Hypoglycemia, Patient Participation
3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Trial
  2. Article
  3. Article
  4. Observational
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Dulce CanhaDeep Digital Phenotyping Research Unit, Department of Precision Health, Luxembourg Institute of Health, Strassen, Luxembourg.ORCID http://orcid.org/0009-0004-4763-1026
Gloria AguayoDeep Digital Phenotyping Research Unit, Department of Precision Health, Luxembourg Institute of Health, Strassen, Luxembourg.ORCID http://orcid.org/0000-0002-5625-1664
Emmanuel CossonDepartment of Endocrinology-Diabetology-Nutrition, AP-HP, Avicenne Hospital, Bobigny, France.ORCID http://orcid.org/0000-0002-8785-3385
Patricia VaduvaDepartment of Endocrinology, Diabetes and Nutrition, Rennes University Hospital, Rennes, France.
Eric RenardDepartment of Endocrinology, Diabetes, Nutrition, Montpellier University Hospital, Montpellier, France.ORCID http://orcid.org/0000-0002-3407-7263
Fawaz AlzaidInstitut Necker-Enfants Malades, INSERM U1151, CNRS UMR 8253, IMMEDIAB Laboratory, Paris, France.
Fabrice BonnetDepartment of Diabetology, CHU de Rennes, Rennes, France.
Samy HadjadjInstitut du Thorax, CHU Nantes, Nantes, France.
Louis PotierInstitut Necker-Enfants Malades, INSERM U1151, CNRS UMR 8253, IMMEDIAB Laboratory, Paris, France.
Bruno VergèsDepartment of Endocrinology‑Diabetology, Inserm LNC UMR1231, University of Burgundy, Dijon, France.
Sandrine LablancheDepartment of Diabetology, Endocrinology and Nutrition, Grenoble Alpes University Hospital, Inserm U1055, Grenoble, France.
Pierre Yves BenhamouUniversité Grenoble Alpes, Inserm U1055, CHU Grenoble Alpes, Grenoble, France.ORCID http://orcid.org/0000-0003-4378-0468
Helene HanaireDepartment of Diabetology, Metabolic Diseases and Nutrition, CHU Toulouse, University of Toulouse, Toulouse, France.
Yves ReznikEndocrinology and Diabetes Department, CHU Côte de Nacre, Caen, France.ORCID http://orcid.org/0000-0002-6267-8058
Jean-Pierre RivelineInstitut Necker-Enfants Malades, INSERM U1151, CNRS UMR 8253, IMMEDIAB Laboratory, Paris, France.
Guy FagherazziDeep Digital Phenotyping Research Unit, Department of Precision Health, Luxembourg Institute of Health, Strassen, Luxembourg Guy.Fagherazzi@lih.lu.ORCID http://orcid.org/0000-0001-5033-5966

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionType 1 diabetes is burdensome, requiring complex daily management and making people more prone to emotional distress. To better detect diabetes-related distress (DD) and identify at-risk patients, we aimed to provide an in-depth characterization of DD in people with type 1 diabetes. RESEARCH DESIGN AND

methodsWe included adults with type 1 diabetes from the

resultsIn total, 1220 participants (50.6% female, age 42 years (SD 13.9), diabetes duration 24.7 years (13.6)) had a total mean PAID score of 39.6 (21.7) and 592 (48.5%) reported high DD. Leading subdimensions of DD included fear of complications (50.1 (24.4)) and diabetes burnout (45.9 (24.5)). Females, younger age, social vulnerability, smoking, and the presence of retinopathy were positively associated with high DD (p<0.05). We observed similar DD levels across HbA1c levels and treatment modalities, including automated insulin delivery and continuous glucose monitoring use. Several psychological factors, such as anxiety/depression, poor sleep quality, and treatment burden, were strongly associated with DD (p<0.001).

conclusionsWe provide a holistic clinical phenotyping approach that enables the identification of determinants and prevalence of DD, overall and according to key DD subdimensions, in a large and diverse population. Our results underscore the importance of developing DD-targeted prevention and intervention strategies focused specifically on high-risk groups and the most impactful distress subdimensions to reduce the impact of type 1 diabetes burden. TRIAL REGISTRATION NUMBER: NCT04657783.

Indexed as

BiomarkersDiabetes ComplicationsDiabetes Mellitus, Type 1Psychological DistressStress, PsychologicalAdultCohort StudiesFemaleFollow-Up StudiesFranceHumansMaleMiddle AgedPhenotypePrognosisSurveys and QuestionnairesBiomarkersAdultDiabetes Mellitus, Type 1PhenotypePsychology

Identifiers

PMID40000027
PMCPMC11865782

What Socratic holds

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LicenceCC BY-NC
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.