Evidence map›Paper›PMID 40000476›Full record

ArticleMikrochimica acta2025

Fluorescent/colorimetric dual-mode for detecting of MC-LR using bidirectional RCA coupled with CdTe QDs.

Weiqing Sun, Xinru Ren, Yijing Xiao, Bowen Li, Qing-Ao Pang, Meili Yang, Rui Zhu, Zhiqiang Guo, Jinghua Yu, Jiadong Huang and 2 more

Abstract read
PubMed Publisher
In one paragraph

Article in Mikrochimica acta, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Weiqing SunSchool of Water Conservancy and Environment, University of Jinan, Jinan, 250022, People's Republic of China.
Xinru RenSchool of Chemistry and Chemical Engineering, University of Jinan, Jinan, 250022, People's Republic of China.
Yijing XiaoSchool of Water Conservancy and Environment, University of Jinan, Jinan, 250022, People's Republic of China.
Bowen LiSchool of Biological Sciences and Technology, University of Jinan, Jinan, 250022, People's Republic of China.
Qing-Ao PangSchool of Biological Sciences and Technology, University of Jinan, Jinan, 250022, People's Republic of China.
Meili YangSchool of Biological Sciences and Technology, University of Jinan, Jinan, 250022, People's Republic of China.
Rui ZhuSchool of Biological Sciences and Technology, University of Jinan, Jinan, 250022, People's Republic of China.
Zhiqiang GuoSchool of Chemistry and Chemical Engineering, University of Jinan, Jinan, 250022, People's Republic of China.
Jinghua YuSchool of Chemistry and Chemical Engineering, University of Jinan, Jinan, 250022, People's Republic of China.
Jiadong HuangSchool of Biological Sciences and Technology, University of Jinan, Jinan, 250022, People's Republic of China.
Yu WangSchool of Biological Sciences and Technology, University of Jinan, Jinan, 250022, People's Republic of China.
Su LiuSchool of Water Conservancy and Environment, University of Jinan, Jinan, 250022, People's Republic of China. stu_lius@ujn.edu.cn.

Funding

National Natural Science Foundation of China 32072330Natural Science Foundation of Shandong Province ZR2022MB066Program for Taishan Scholar of Shandong Province ts201712048
6 · The paper itself

Abstract

A fluorescent/colorimetric dual-mode biosensor was designed using CdTe QDs and CRISPR/Cas for the efficient and ultrasensitive detection of microcystin-leucine-arginine (MC-LR). The biosensor mainly activates the trans-cleavage activity of Cas12a through nucleic acid amplification technology, such as bidirectional rolling circle amplification (B-RCA), to perform signal conversion, release Ag

Indexed as

Biosensing TechniquesCadmium CompoundsColorimetryMicrocystinsNucleic Acid Amplification TechniquesQuantum DotsTelluriumCRISPR-Cas SystemsFluorescent DyesLimit of DetectionMarine ToxinsSpectrometry, FluorescenceCadmium Compoundscadmium telluridecyanoginosin LRFluorescent DyesMarine ToxinsMicrocystinsTelluriumAptamerB-RCAColorimetric detectionCRISPR/CasFluorescence detectionMC-LRQDs

Identifiers

PMID40000476

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.